Clinical studies

Are you very stressed out?

We are looking for generally healthy men and women (who do not take any hormonal contraception) aged 35 to 55 years old, who are stressed on a daily basis, to participate in a research study.

Study on memory, hormones and Alzheimer's disease

•         Natasha Rajah’s laboratory is investigating how biological sex, menopausal status in women, and genetic risk factors for Alzheimer's disease (such as apolipoprotein E4 [ApoE4]) influence brain activity, brain structure and memory in healthy adults (18-75 years). In other words, we want to examine if there are sex differences in memory and brain function at midlife. Also, verify the impact of certain genes on memory and brain function.

•         In addition, we wish to investigate how hormonal changes during menopausal transition affect memory and brain function in middle-aged women.

•         We hope our results will improve our understanding of the influence of aging and genetic risk factors for Alzheimer's disease on memory and brain function in middle-aged adults.

Study: Sleep and circadian rhythms in men and women

RESEARCH PARTICIPANTS WANTED

Study on Sleep and circadian rhythms in men and women

Postmenopausal women 45 years or older wanted for study on sleep-wake cycle. Participants will receive financial compensation for their participation in this study. They will first visit the lab at various times throughout the screening procedure (duration of these visits vary among participants), including 1 night in laboratory for sleep evaluation. They will have 2 periods of 2 weeks at home each to complete questionnaires and 2 lab visit (about 72h visits spanning 4 days). 

Risks and discomforts: blood samples, frequent visits, and overnight stays in our research Centre. For research purposes, participants will be asked to take melatonin, approved by Health Canada to treat sleep-wake disorders, and placebo, a substance that looks like melatonin but doesn’t have any active ingredient.

The effects of sleep restriction/extension on children with ADHD: What a difference an hour makes?

Sleep is essential for a child’s ability to pay attention and regulate behaviour during the day. The goal of the study is to determine whether children can improve their attention and behaviour by sleeping more, and whether an insufficient amount of sleep is a factor that affects their difficulties during the day.

 

Predictive factors of outcome following a Major Depressive Episode in adolescents: a prospective clinical, neurocognitive and neuroimaging study

We are currently conducting a research project on the evolution of depressive symptoms in order to study factors associated with depression.

The ultimate goal of this study is to develop better methods to treat adolescents and young adults with depression and prevent suicide.

Study on alcohol and safe driving

We are currently looking at the effects of alcohol intake on safe driving.

Clinical and pharmacogenetic study of Attention-Deficit/Hyperactivity disorder (ADHD)

Our team of researchers specializing in the field of ADHD includes child psychiatrists, psychologists and a psychiatric geneticist, and explores the causes of ADHD in children, in order to develop better treatments.

Prevent-Alzheimer

Our goal is to understand how we can slow or reverse the emergence of AD symptoms. Your participation will let us study how to prevent declines in brain health. Without the participation of research volunteers, such studies are impossible.


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  • Douglas Hospital
  • Dobell Pavillion
  • Brain imaging centre