Magnetoencephalography in Psychosis program (MEGPSY): Temporal Regularity on Neural Activity and its relationship to psychotic symptoms

Principal Investigator

Dr Lena Palaniyappan, MD, PhD, FRCPC

Description of study

Both speech comprehension and production are affected in schizophrenia. Patients produce peculiar and sentences that are out of context and unpredictable, leading to a communication impairment. It is therefore essential to understand the neural mechanisms at the origin of this disorder and their relationship to these symptoms. MEGPSY aims to investigate the brain’s role in communication problems among peoples with schizophrenia, by combining bioimaging and speech analysis.

This study involves the examination of speech, thinking patterns and symptoms, as well as recordings of brain activity through Magnetoencephalography (MEG) and Magnetic Resonance Imaging (MRI).

We are currently recruiting healthy controls participants.

For eligibility criteria and more information, please read the following Brochure: MEGPSY-advertisement For Healthy Controls

Financial compensation



Study Requirements & Procedures:

If you are eligible for our study, we will invite you to do the following during 1 study visit of up to 4 hours.

  • Speech tasks
  • Audio-visual tasks
  • Non-invasive brain imaging (MRI & MEG scanning)



The study will take place at the McConnell Brain Imaging Centre at the Montreal Neurological Institute.


Your participation will contribute to a better understanding of the nature of mental illness which may lead to earlier intervention and the development of better treatments.


If you have any question or are interested in participating, please contact:

Nadia Zeramdini
Study Research Coordinator, Douglas Mental Health University Institute

Tel: (514) 761-6131, ext. 3204