Stress, Anxiety, Depression, and Suicide


Leader: Naguib Mechawar, PhD

For decades, research on stress and stress-related disorders has been one of the core strengths of the Douglas Research Centre. We  bring together a group of investigators who are exploring the nature and consequences of stress exposure during different stages of life. These investigators, who are spread across the Centre’s four divisions, use a wide range of approaches including (but not limited to) basic research with animal models and human tissue samples, and clinical and psychosocial research. By studying various dimensions of stress, resilience to stress and stress-related psychopathologies, their main objective is, ultimately, to improve prevention and treatment.


Research Program

The overarching goals of Stress, Anxiety, Depression, and Suicide​ are the following.

  1. Better understand the functional consequences of chronic stress and the nature of resilience at the cellular, molecular and behavioral levels.
  2. Identify the environmental and biological factors associated with vulnerability or resilience to chronic stress.
  3. Develop better evidence-based interventions and policies aimed at preventing and treating stress-related mental illnesses.

Primary Researchers

Jorge Armony

Jorge Armony

Emotions, fMRI, PTSD
Serge Beaulieu

Serge Beaulieu

Programme des troubles bipolaires
Marcelo Berlim

Marcelo Berlim

Neuromodulation Research Clinic
Alain Brunet

Alain Brunet

Impact of traumatic stress on mental health
Eduardo Chachamovich

Eduardo Chachamovich

Social and clinical determinants of mental health in Aboriginal populations
Salah El-Mestikawy

Salah El Mestikawy

Glutamatergic systems in normal and pathological brains

Bruno Giros

Pathophysiology of psychiatric disorders
Alain Gratton, PhD

Alain Gratton

Neurobiology of stress
Naguib Mechawar, PhD

Naguib Mechawar

Neuroanatomy of mood disorders and suicide
Corina Nagy

Corina Nagy

Neuromolecular and brain cell specific underpinnings of mood disorders

Massimiliano Orri

Understanding the risk factors for suicidal behaviour across the lifespan
Johanne Renaud

Johanne Renaud

Youth suicide and suicidal behaviours
Stéphane Richard-Devantoy, MD, PhD

Stéphane Richard-Devantoy

Cognitive Control, Depression, and Suicide in the Elderly
Joseph Rochford, PhD

Joseph Rochford

Animal models, behavioral pharmacology, behavioural phenotyping

Gustavo Turecki

Suicide studies
Tak Pan Wong, PhD

Tak Pan Wong

Glutamate synapses and psychiatric disorders

Associated Researchers


Linda Booij

Eating Disorders Continuum

Cecilia Flores

Adolescent brain development and susceptibility to psychopathology

Marie-Claude Geoffroy

Longitudinal epidemiology of suicide and related mental disorders accross the lifespan and interventions to promote mental health
Mimi Israel, MD, MSc

Mimi Israel

Eating disorders
Suzanne King, PhD

Suzanne King

Role of prenatal maternal stress in the development of psychopathology

Howard Steiger

Eating Disorders Program