The hippocampus retains the traces of negative stressful experiences that can lead to depression-related behaviors.

An article by Dr. Tak Pan Wong of the Douglas Research Centre, a professor in the McGill’s Department of Psychiatry, was published today in the Journal of Neuroscience. This study used a mouse model of depression using social stress to show that a biological marker in the hippocampus could explain some of the cognitive difficulties that are frequently associated with depression.