Is there an association between neurocognitive performance and medication adherence in first episode psychosis?
|Title||Is there an association between neurocognitive performance and medication adherence in first episode psychosis?|
|Publication Type||Journal Article|
|Year of Publication||2010|
|Authors||Lepage M, Bodnar M, Joober R, Malla A|
|Journal||Early Interv Psychiatry|
|Date Published||2010 May|
AIM: Medication adherence is a determining factor for symptomatic remission and relapse prevention following a first episode of psychosis (FEP). Neurocognitive abilities have received only scant attention so far as a risk factor for poor adherence but significant impairments with memory and/or planning abilities could play a role. We examined early medication adherence following admission to a specialized clinical programme for FEP.METHOD: One hundred sixty FEP participants and 35 healthy controls completed an exhaustive neurocognitive assessment. FEP participants were categorized as a function of their medication adherence at 6 months into poor (n = 34), partial (n = 27) and full (n = 99) adherence, respectively. Domain-specific and global measures of cognitive ability were examined.RESULTS: No measure of neurocognition could significantly discriminate amongst the three medication adherence groups.CONCLUSION: These results suggest no strong associations between neurocognitive abilities and medication adherence in first episode of psychosis.
|Alternate Journal||Early Interv Psychiatry|
|Grant List||68961 / / Canadian Institutes of Health Research / Canada|