Study on memory, hormones and Alzheimer's disease
Maria Natasha Rajah
• Natasha Rajah’s laboratory is investigating how biological sex, menopausal status in women, and genetic risk factors for Alzheimer's disease (such as apolipoprotein E4 [ApoE4]) influence brain activity, brain structure and memory in healthy adults (18-75 years). In other words, we want to examine if there are sex differences in memory and brain function at midlife. Also, verify the impact of certain genes on memory and brain function.
• In addition, we wish to investigate how hormonal changes during menopausal transition affect memory and brain function in middle-aged women.
• We hope our results will improve our understanding of the influence of aging and genetic risk factors for Alzheimer's disease on memory and brain function in middle-aged adults.
- Complete a medical questionnaire (available online at http://www.ugd-dmu.ca/memory)
- Participation in this study involves two visits to the Douglas Institute in Verdun (2.5 hours each).
- You will have to perform a series of memory tests on paper and computer.
- We will take a blood sample to measure your hormone levels and study the association between certain genes and memory.
- You will be subjected to magnetic resonance imaging (MRI) simulation
- You will need to perform memory tests in a magnetic resonance imaging (MRI) device.
- You will contribute to the advancement of research in mental health
- Age: 18 to 75 years old
- Work: works full time or is temporarily out of work (less than 6 months)
- Education: Completed High School
- Bilingual (one language has to be English or French)
- No history of mental illness
- No history of diabetes
- No history of stroke