Raspberry neurons swimming in the brain
Laura Joy Boulos
Description and scientific context:
In this picture, we see three different populations of berry-coloured habenular neurons. The habenula is a central brain structure that acts as a true hub connecting the forebrain to the midbrain. It is also the brain structure that shows the highest density of mu opioid receptors (MORs) –the main target of opiates and other drugs of abuse. In our experiment, we counted the number of colocalization between MORs and the two major neurotransmitters in the habenula: acetylcholine and substance P. The result allowed us to characterize the neuronal population of the habenula underlying addiction mechanisms.
Specimen and labels:
fluorescently-labelled neurons in a fresh-frozen brain from a mouse habenula
The Olympus Slide Scanner, 40x magnification