Publications

Export 19 results:
Author Title [ Type(Desc)] Year
Filters: Author is Darcq, Emmanuel  [Clear All Filters]
Journal Article
Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M et al..  2019.  Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons.. iScience. 14:47-57.
Moore K, Madularu D, Iriah S, Yee JR, Kulkarni P, Darcq E, Kieffer BL, Ferris CF.  2016.  BOLD Imaging in Awake Wild-Type and Mu-Opioid Receptor Knock-Out Mice Reveals On-Target Activation Maps in Response to Oxycodone.. Front Neurosci. 10:471.
Nasseef MTaufiq, Ma W, Singh JPuneet, Dozono N, Lançon K, Séguéla P, Darcq E, Ueda H, Kieffer BL.  2021.  Chronic generalized pain disrupts whole brain functional connectivity in mice.. Brain Imaging Behav.
Darcq E, Kieffer BL.  2018.  The Control of Reward Seeking.. Biol Psychiatry. 83(12):981-983.
Nasseef MTaufiq, Devenyi GA, Mechling AE, Harsan L-A, Chakravarty MM, Kieffer BL, Darcq E.  2018.  Deformation-based Morphometry MRI Reveals Brain Structural Modifications in Living Mu Opioid Receptor Knockout Mice.. Front Psychiatry. 9:643.
Mechling AE, Arefin T, Lee H-L, Bienert T, Reisert M, Ben Hamida S, Darcq E, Ehrlich A, Gaveriaux-Ruff C, Parent MJ et al..  2016.  Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome.. Proc Natl Acad Sci U S A. 113(41):11603-11608.
Chung PChu Sin, Boehrer A, Stephan A, Matifas A, Scherrer G, Darcq E, Befort K, Kieffer BL.  2015.  Delta opioid receptors expressed in forebrain GABAergic neurons are responsible for SNC80-induced seizures.. Behav Brain Res. 278:429-34.
Rahman MToufiqur, Decker AM, Langston TL, Mathews KM, Laudermilk L, Maitra R, Ma W, Darcq E, Kieffer BL, Jin C.  2020.  Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.. J Med Chem. 63(23):14989-15012.
Jin C, Decker AM, Makhijani VH, Besheer J, Darcq E, Kieffer BL, Maitra R.  2018.  Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake.. J Med Chem. 61(15):6748-6758.
Ben Hamida S, Mendonça-Netto S, Arefin TMahmud, Nasseef MTaufiq, Boulos L-J, McNicholas M, Ehrlich AToby, Clarke E, Moquin L, Gratton A et al..  2018.  Increased Alcohol Seeking in Mice Lacking Gpr88 Involves Dysfunctional Mesocorticolimbic Networks.. Biol Psychiatry.
Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M et al..  2018.  Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.. Brain Struct Funct. 223(3):1275-1296.
Charbogne P, Gardon O, Martin-Garcia E, Keyworth HL, Matsui A, Mechling AE, Bienert T, Nasseef T, Robé A, Moquin L et al..  2017.  Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food.. Biol Psychiatry. 81(9):778-788.
Welsch L, Bailly J, Darcq E, Kieffer BL.  2019.  The Negative Affect of Protracted Opioid Abstinence: Progress and Perspectives From Rodent Models.. Biol Psychiatry.
Chung PChu Sin, Keyworth HL, Martin-Garcia E, Charbogne P, Darcq E, Bailey A, Filliol D, Matifas A, Scherrer G, Ouagazzal A-M et al..  2015.  A novel anxiogenic role for the delta opioid receptor expressed in GABAergic forebrain neurons.. Biol Psychiatry. 77(4):404-15.
Darcq E, Kieffer BL.  2018.  Opioid receptors: drivers to addiction? Nat Rev Neurosci. 19(8):499-514.
Nasseef MTaufiq, Singh JPuneet, Ehrlich AT, McNicholas M, Park DWoon, Ma W, Kulkarni P, Kieffer BL, Darcq E.  2019.  Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice.. ACS Pharmacol Transl Sci. 2(4):264-274.
Darcq E, Kieffer BL.  2015.  PI3K signaling in the locus coeruleus: a new molecular pathway for ADHD research.. EMBO Mol Med. 7(7):859-61.
Bailly J, Del Rossi N, Runtz L, Li J-J, Park DW, Scherrer G, Tanti A, Birling M-C, Darcq E, Kieffer BL.  2020.  Targeting Morphine-Responsive Neurons: Generation of a Knock-In Mouse Line Expressing Cre Recombinase from the Mu-Opioid Receptor Gene Locus.. eNeuro. 7(3)
Boulos L-J, Darcq E, Kieffer BL.  2017.  Translating the Habenula-From Rodents to Humans.. Biol Psychiatry. 81(4):296-305.