Publications

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Journal Article
Cruceanu C, Tan PPatrick Ch, Rogic S, Lopez JPablo, Torres-Platas SGabriela, Gigek CO, Alda M, Rouleau GA, Pavlidis P, Turecki G.  2015.  Transcriptome sequencing of the anterior cingulate in bipolar disorder: dysregulation of G protein-coupled receptors.. Am J Psychiatry. 172(11):1131-40.
Cruceanu C, Alda M, Dion PA, Turecki G, Rouleau GA.  2015.  No evidence for GADL1 variation as a bipolar disorder susceptibility factor in a Caucasian lithium-responsive cohort.. Am J Psychiatry. 172(1):94-5.
Squassina A, Niola P, Lopez JPablo, Cruceanu C, Pisanu C, Congiu D, Severino G, Ardau R, Chillotti C, Alda M et al..  2020.  MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings.. Eur Neuropsychopharmacol. 34:39-49.
Niola P, Gross JA, Lopez JPablo, Chillotti C, Deiana V, Manchia M, Georgitsi M, Patrinos GP, Alda M, Turecki G et al..  2014.  Lithium-induced differential expression of SAT1 in suicide completers and controls is not correlated with polymorphisms in the promoter region of the gene.. Psychiatry Res. 220(3):1167-8.
Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M et al..  2018.  Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.. Bipolar Disord.
Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NMenjot et al..  2017.  Implication of LRRC4C and DPP6 in neurodevelopmental disorders.. Am J Med Genet A. 173(2):395-406.
Forstner AJ, Hecker J, Hofmann A, Maaser A, Reinbold CS, Mühleisen TW, Leber M, Strohmaier J, Degenhardt F, Treutlein J et al..  2017.  Identification of shared risk loci and pathways for bipolar disorder and schizophrenia.. PLoS One. 12(2):e0171595.
Le Clerc S, Lombardi L, Baune BT, Amare AT, Schubert KOliver, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U et al..  2021.  HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders.. Sci Rep. 11(1):17823.
Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Forstner AJ, Schumacher J, Breuer R et al..  2014.  Genome-wide association study reveals two new risk loci for bipolar disorder.. Nat Commun. 5:3339.
Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landen M, Adli M, Alda M, Ardau R, Arias B et al..  2016.  Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.. Hum Mol Genet. 25(15):3383-3394.
Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CEM et al..  2016.  Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.. Lancet. 387(10023):1085-93.
Mühleisen TW, Reinbold CS, Forstner AJ, Abramova LI, Alda M, Babadjanova G, Bauer M, Brennan P, Chuchalin A, Cruceanu C et al..  2018.  Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder.. J Affect Disord. 228:20-25.
Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AArias, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B et al..  2014.  The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.. Brain Imaging Behav. 8(2):153-82.
Cruceanu C, Kutsarova E, Chen ES, Checknita DR, Nagy C, Lopez JPablo, Alda M, Rouleau GA, Turecki G.  2016.  DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression.. BMC Psychiatry. 16(1):286.
Mullins N, Kang JE, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A et al..  2022.  Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.. Biol Psychiatry. 91(3):313-327.
Huzayyin AA, Andreazza AC, Turecki G, Cruceanu C, Rouleau GA, Alda M, L Young T.  2014.  Decreased global methylation in patients with bipolar disorder who respond to lithium.. Int J Neuropsychopharmacol. 17(4):561-9.
Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NMenjot et al..  2017.  Cover Image, Volume 173A, Number 2, February 2017.. Am J Med Genet A. 173(2):i.
Schubert KOliver, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B et al..  2021.  Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.. Transl Psychiatry. 11(1):606.
Yatham LN, Kennedy SH, O'Donovan C, Parikh S, MacQueen G, McIntyre R, Sharma V, Silverstone P, Alda M, Baruch P et al..  2005.  Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies.. Bipolar Disord. 7 Suppl 3:5-69.
Amare AT, Schubert KOliver, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu Y-H, Shekhtman T et al..  2018.  Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.. JAMA Psychiatry. 75(1):65-74.
Amare AT, Schubert KOliver, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu Y-H et al..  2020.  Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.. Mol Psychiatry.
Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K et al..  2018.  Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.. Front Psychiatry. 9:207.
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R et al..  2018.  Analysis of shared heritability in common disorders of the brain.. Science. 360(6395)