Publications
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Filters: Author is Brigitte L Kieffer [Clear All Filters]
Focusing on the Opioid System for Addiction Biomarker Discovery.. Trends Mol Med. 24(2):206-220.
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2018. Increased Alcohol Seeking in Mice Lacking Gpr88 Involves Dysfunctional Mesocorticolimbic Networks.. Biol Psychiatry.
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2018. Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats.. Neuropsychopharmacology.
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2018. Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.. Brain Struct Funct. 223(3):1275-1296.
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2018. Opioid receptors: drivers to addiction? Nat Rev Neurosci. 19(8):499-514.
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2018. Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists.. Sci Signal. 12(574)
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2019. An Anti-Opioid System, Courtesy of a Worm Model.. N Engl J Med. 381(21):2067-2069.
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2019. Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons.. iScience. 14:47-57.
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2019. Mu and delta opioid receptors play opposite nociceptive and behavioural roles on nerve-injured mice.. Br J Pharmacol.
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2019. The Negative Affect of Protracted Opioid Abstinence: Progress and Perspectives From Rodent Models.. Biol Psychiatry.
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2019. Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice.. ACS Pharmacol Transl Sci. 2(4):264-274.
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Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.. J Med Chem. 63(23):14989-15012.
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2020. Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia.. Sci Rep. 10(1):17629.
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2020. NOP receptor agonist attenuates nitroglycerin-induced migraine-like symptoms in mice.. Neuropharmacology. 170:108029.
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2020. Ackr3-Venus knock-in mouse lights up brain vasculature.. Mol Brain. 14(1):151.
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2021. Chronic generalized pain disrupts whole brain functional connectivity in mice.. Brain Imaging Behav. 15(5):2406-2416.
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2021. Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.. J Med Chem. 64(16):12397-12413.
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2021. Increased functional coupling of the mu opioid receptor in the anterior insula of depressed individuals.. Neuropsychopharmacology. 46(5):920-927.
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2021. Mapping the living mouse brain neural architecture: strain-specific patterns of brain structural and functional connectivity.. Brain Struct Funct. 226(3):647-669.
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