Publications
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18F-MK-6240 PET for early and late detection of neurofibrillary tangles.. Brain. 143(9):2818-2830.
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2020. Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease.. Eur J Nucl Med Mol Imaging. 45(6):1021-1030.
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2018. Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer's disease.. Mol Psychiatry.
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2020. Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia.. Ann Clin Transl Neurol. 8(10):2083-2092.
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2021. Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.. Neurology. 90(11):e932-e939.
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Epistasis analysis links immune cascades and cerebral amyloidosis.. J Neuroinflammation. 12:227.
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2015. Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, ε4, and Cognitive Impairment.. Neurology. 96(7):e975-e985.
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2021. Identifying incipient dementia individuals using machine learning and amyloid imaging.. Neurobiol Aging. 59:80-90.
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2017. In vivo quantification of neurofibrillary tangles with [F]MK-6240.. Alzheimers Res Ther. 10(1):74.
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2018. Interactive rather than independent effect of and sex potentiates tau deposition in women.. Brain Commun. 3(2):fcab126.
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2021. Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.. Brain. 144(11):3517-3528.
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2021. Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(9):1592-1599.
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2021. Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.. Neurology. 88(19):1814-1821.
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2017. Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies.. Stat Methods Med Res.
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2016. Publisher Correction: Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(11):2048-2049.
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2021. Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [F]THK5351 uptake in progressive supranuclear palsy.. Neuroimage Clin. 24:102091.
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2019. Serum and cerebrospinal fluid biomarker profiles in acute SARS-CoV-2-associated neurological syndromes.. Brain Commun. 3(3):fcab099.
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2021. Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.. Cell Biosci. 11(1):204.
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2021. Synergistic interaction between amyloid and tau predicts the progression to dementia.. Alzheimers Dement. 13(6):644-653.
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variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.. Neurol Genet. 4(1):e216.
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2018. VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis.. Front Neuroinform. 10:20.
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