Publications

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Lin M-S, Xiong W-C, Li S-J, Gong Z, Cao X, Kuang X-J, Zhang Y, Gao T-M, Mechawar N, Liu C et al..  2017.  α2-glycine receptors modulate adult hippocampal neurogenesis and spatial memory.. Dev Neurobiol. 77(12):1430-1441.
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O'Leary LAnuj, Belliveau C, Davoli MAntonietta, Ma JChristophe, Tanti A, Turecki G, Mechawar N.  2021.  Widespread Decrease of Cerebral Vimentin-Immunoreactive Astrocytes in Depressed Suicides.. Front Psychiatry. 12:640963.
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Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A et al..  2018.  Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.. Nat Commun. 9(1):2459.
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Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Théroux J-F, Moquin L et al..  2020.  Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.. Stem Cells Transl Med. 9(6):697-712.
Nagy C, Maitra M, Tanti A, Suderman M, Théroux J-F, Davoli MAntonietta, Perlman K, Yerko V, Wang YChang, Tripathy SJ et al..  2020.  Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons.. Nat Neurosci. 23(6):771-781.
Kaul D, Smith CC, Stevens J, Fröhlich AS, Binder EB, Mechawar N, Schwab SG, Matosin N.  2020.  Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders.. Neurobiol Stress. 13:100270.
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Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu AP, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM et al..  2019.  Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration.. Sci Rep. 9(1):7850.
Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM et al..  2018.  Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor.. Neuroimage. 176:226-238.
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Lutz P-E, Chay M-A, Pacis A, Chen GG, Aouabed Z, Maffioletti E, Théroux J-F, Grenier J-C, Yang J, Aguirre M et al..  2021.  Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation.. Nat Commun. 12(1):1132.
Hökfelt T, Barde S, Xu Z-QDavid, Kuteeva E, Rüegg J, Le Maitre E, Risling M, Kehr J, Ihnatko R, Theodorsson E et al..  2018.  Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness.. Front Neural Circuits. 12:106.
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Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Théroux J-F, Jefri M, Tanti A, Wu H, Kolobova I et al..  2019.  Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.. Am J Hum Genet. 104(5):815-834.
Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Théroux J-F, Jefri M, Tanti A, Wu H, Kolobova I et al..  2019.  Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons. The American Journal of Human Genetics.
Poirel O, Mella S, Videau C, Ramet L, Davoli MAntonietta, Herzog E, Katsel P, Mechawar N, Haroutunian V, Epelbaum J et al..  2018.  Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages.. Sci Rep. 8(1):938.
Fiori LM, Kos A, Lin R, Théroux J-F, Lopez JPablo, Kühne C, Eggert C, Holzapfel M, Huettl R-E, Mechawar N et al..  2020.  miR-323a regulates ERBB4 and is involved in depression.. Mol Psychiatry.
Salamanca L, Mechawar N, Murai KK, Balling R, Bouvier DS, Skupin A.  2019.  MIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples.. Glia. 67(8):1496-1509.
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Kaul D, Schwab SG, Mechawar N, Matosin N.  2021.  How stress physically re-shapes the brain: Impact on brain cell shapes, numbers and connections in psychiatric disorders.. Neurosci Biobehav Rev. 124:193-215.
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Belzeaux R, Gorgievski V, Fiori LM, Lopez JPablo, Grenier J, Lin R, Nagy C, Ibrahim EChérif, Gascon E, Courtet P et al..  2020.  GPR56/ADGRG1 is associated with response to antidepressant treatment.. Nat Commun. 11(1):1635.
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Rocco BR, Oh H, Shukla R, Mechawar N, Sibille E.  2017.  Fluorescence-based cell-specific detection for laser-capture microdissection in human brain.. Sci Rep. 7(1):14213.
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Tanti A, Lutz P-E, Kim J, O'Leary L, Théroux J-F, Turecki G, Mechawar N.  2019.  Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides.. Neuropsychopharmacology. 44(12):2099-2111.
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Bell S, Maussion G, Jefri M, Peng H, Théroux J-F, Silveira H, Soubannier V, Wu H, Hu P, Galat E et al..  2018.  Disruption of GRIN2B Impairs Differentiation in Human Neurons.. Stem Cell Reports. 11(1):183-196.
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Belleville S, LeBlanc AC, Kergoat M-J, Calon F, Gaudreau P, Hébert SS, Hudon C, Leclerc N, Mechawar N, Duchesne S et al..  2019.  The Consortium for the early identification of Alzheimer's disease-Quebec (CIMA-Q).. Alzheimers Dement (Amst). 11:787-796.
Vaillancourt K, Yang J, Chen GG, Yerko V, Théroux J-F, Aouabed Z, Lopez A, Thibeault KC, Calipari ES, Labonte B et al..  2020.  Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster.. Mol Psychiatry.
O'Leary LAnuj, Davoli MAntonietta, Belliveau C, Tanti A, Ma JChristophe, Farmer WTodd, Turecki G, Murai KKazuo, Mechawar N.  2020.  Characterization of Vimentin-Immunoreactive Astrocytes in the Human Brain.. Front Neuroanat. 14:31.
Faria TC, Maldonado HL, Santos LC, Delabio R, Payão SLM, Turecki G, Mechawar N, Santana DA, Gigek CO, Lemos B et al..  2020.  Characterization of Cerebellum-Specific Ribosomal DNA Epigenetic Modifications in Alzheimer's Disease: Should the Cerebellum Serve as a Control Tissue After All? Mol Neurobiol. 57(6):2563-2571.
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Han S, Yang SHyun, Kim JYong, Mo S, Yang E, Song KMyung, Ham B-J, Mechawar N, Turecki G, Lee HWoo et al..  2017.  Author Correction: Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.. Sci Rep. 7(1):17090.

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