Publications

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2019
Pizzagalli DA, Berretta S, Wooten D, Goer F, Pilobello KT, Kumar P, Murray L, Beltzer M, Boyer-Boiteau A, Alpert N et al..  2019.  Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence.. JAMA Psychiatry.
Xiong W, Cao X, Zeng Y, Qin X, Zhu M, Ren J, Wu Z, Huang Q, Zhang Y, Wang M et al..  2019.  Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors.. J Neurosci. 39(23):4606-4623.
Tanti A, Lutz P-E, Kim J, O'Leary L, Théroux J-F, Turecki G, Mechawar N.  2019.  Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides.. Neuropsychopharmacology. 44(12):2099-2111.
Salamanca L, Mechawar N, Murai KK, Balling R, Bouvier DS, Skupin A.  2019.  MIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples.. Glia. 67(8):1496-1509.
Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Théroux J-F, Jefri M, Tanti A, Wu H, Kolobova I et al..  2019.  Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.. Am J Hum Genet. 104(5):815-834.
Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Théroux J-F, Jefri M, Tanti A, Wu H, Kolobova I et al..  2019.  Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons. The American Journal of Human Genetics.
Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu AP, Lerch JP, Elgbeili G, Courcot B, Mechawar N, M Chakravarty M et al..  2019.  Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration.. Sci Rep. 9(1):7850.
2018
Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JPablo, Grenier J, Ibrahim EChérif, Khoury M-AEl, Tse YC, Mongredien R et al..  2018.  Antidepressive effects of targeting ELK-1 signal transduction.. Nat Med. 24(5):591-597.
Bell S, Maussion G, Jefri M, Peng H, Théroux J-F, Silveira H, Soubannier V, Wu H, Hu P, Galat E et al..  2018.  Disruption of GRIN2B Impairs Differentiation in Human Neurons.. Stem Cell Reports. 11(1):183-196.
Poirel O, Mella S, Videau C, Ramet L, Davoli MAntonietta, Herzog E, Katsel P, Mechawar N, Haroutunian V, Epelbaum J et al..  2018.  Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages.. Sci Rep. 8(1):938.
Hökfelt T, Barde S, Xu Z-QDavid, Kuteeva E, Rüegg J, Le Maitre E, Risling M, Kehr J, Ihnatko R, Theodorsson E et al..  2018.  Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness.. Front Neural Circuits. 12:106.
Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch JP, Elgbeili G, Courcot B, Mechawar N, M Chakravarty M et al..  2018.  Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor.. Neuroimage. 176:226-238.
Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A et al..  2018.  Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.. Nat Commun. 9(1):2459.
2017
Lutz P-E, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D et al..  2017.  Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence.. Am J Psychiatry. :appiajp201716111286.
Han S, Yang SHyun, Kim JYong, Mo S, Yang E, Song KMyung, Ham B-J, Mechawar N, Turecki G, Lee HWoo et al..  2017.  Author Correction: Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.. Sci Rep. 7(1):17090.
Han S, Yang SHyun, Kim JYong, Mo S, Yang E, Song KMyung, Ham B-J, Mechawar N, Turecki G, Lee HWoo et al..  2017.  Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.. Sci Rep. 7(1):900.
Rocco BR, Oh H, Shukla R, Mechawar N, Sibille E.  2017.  Fluorescence-based cell-specific detection for laser-capture microdissection in human brain.. Sci Rep. 7(1):14213.
Chen GG, Gross JA, Lutz P-E, Vaillancourt K, Maussion G, Bramoulle A, Théroux J-F, Gardini ES, Ehlert U, Bourret G et al..  2017.  Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine.. BMC Genomics. 18(1):96.
Lopez JPablo, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C et al..  2017.  MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.. Nat Commun. 8:15497.
Kelaï S, Ramoz N, Moalic J-M, Noble F, Mechawar N, Imbeaud S, Turecki G, Simonneau M, Gorwood P, Maussion G.  2017.  Netrin G1: its downregulation in the nucleus accumbens of cocaine-conditioned mice and genetic association in human cocaine dependence.. Addict Biol.
Pabba M, Scifo E, Kapadia F, Nikolova YS, Ma T, Mechawar N, Tseng GC, Sibille E.  2017.  Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging.. Neurobiol Aging. 58:180-190.
Labonte B, Engmann O, Purushothaman I, Ménard C, Wang J, Tan C, Scarpa JR, Moy G, Loh Y-HE, Cahill M et al..  2017.  Sex-specific transcriptional signatures in human depression.. Nat Med. 23(9):1102-1111.
Lin M-S, Xiong W-C, Li S-J, Gong Z, Cao X, Kuang X-J, Zhang Y, Gao T-M, Mechawar N, Liu C et al..  2017.  α2-glycine receptors modulate adult hippocampal neurogenesis and spatial memory.. Dev Neurobiol. 77(12):1430-1441.
2016
Barde S, Rüegg J, Prud'homme J, Ekström TJ, Palkovits M, Turecki G, Bagdy G, Ihnatko R, Theodorsson E, Juhasz G et al..  2016.  Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide.. Proc Natl Acad Sci U S A. 113(52):E8472-E8481.
Mahar I, MacIsaac A, Kim JJunghan, Qiang C, Davoli MAntonietta, Turecki G, Mechawar N.  2016.  Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis.. Sci Rep. 6:30467.

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