Publications

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A
Barde S, Rüegg J, Prud'homme J, Ekström TJ, Palkovits M, Turecki G, Bagdy G, Ihnatko R, Theodorsson E, Juhasz G et al..  2016.  Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide.. Proc Natl Acad Sci U S A. 113(52):E8472-E8481.
Silva PNatalia, Furuya TKatsue, Braga ILacerda, Rasmussen LTrevizani, Labio RWillian, Bertolucci PHenrique, Chen ESuchi, Turecki G, Mechawar N, Payão SLuiz et al..  2014.  Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients.. J Alzheimers Dis. 38(1):165-70.
Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JPablo, Grenier J, Ibrahim EChérif, Khoury M-AEl, Tse YC, Mongredien R et al..  2018.  Antidepressive effects of targeting ELK-1 signal transduction.. Nat Med. 24(5):591-597.
Pizzagalli DA, Berretta S, Wooten D, Goer F, Pilobello KT, Kumar P, Murray L, Beltzer M, Boyer-Boiteau A, Alpert N et al..  2019.  Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence.. JAMA Psychiatry.
Lutz P-E, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D et al..  2017.  Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence.. Am J Psychiatry. :appiajp201716111286.
Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G.  2015.  Astrocytic abnormalities and global DNA methylation patterns in depression and suicide.. Mol Psychiatry. 20(3):320-8.
Xiong W, Cao X, Zeng Y, Qin X, Zhu M, Ren J, Wu Z, Huang Q, Zhang Y, Wang M et al..  2019.  Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors.. J Neurosci. 39(23):4606-4623.
Han S, Yang SHyun, Kim JYong, Mo S, Yang E, Song KMyung, Ham B-J, Mechawar N, Turecki G, Lee HWoo et al..  2017.  Author Correction: Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.. Sci Rep. 7(1):17090.
C
Devorak J, Torres-Platas SGabriela, Davoli MAntonietta, Prud'homme J, Turecki G, Mechawar N.  2015.  Cellular and Molecular Inflammatory Profile of the Choroid Plexus in Depression and Suicide.. Front Psychiatry. 6:138.
D
Lutz P-E, Zhou Y, Labbe A, Mechawar N, Turecki G.  2015.  Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicides.. Eur Neuropsychopharmacol. 25(11):2008-14.
Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy J-P, Clark SD, Aghourian M, Bedard M-A.  2015.  Deficit in sustained attention following selective cholinergic lesion of the pedunculopontine tegmental nucleus in rat, as measured with both post-mortem immunocytochemistry and in vivo PET imaging with [¹⁸F]fluoroethoxybenzovesamicol.. Behav Brain Res. 278:107-14.
Bell S, Maussion G, Jefri M, Peng H, Théroux J-F, Silveira H, Soubannier V, Wu H, Hu P, Galat E et al..  2018.  Disruption of GRIN2B Impairs Differentiation in Human Neurons.. Stem Cell Reports. 11(1):183-196.
Vigneault E, Poirel O, Riad M, Prud'homme J, Dumas S, Turecki G, Fasano C, Mechawar N, Mestikawy SEl.  2015.  Distribution of vesicular glutamate transporters in the human brain.. Front Neuroanat. 9:23.
Han S, Yang SHyun, Kim JYong, Mo S, Yang E, Song KMyung, Ham B-J, Mechawar N, Turecki G, Lee HWoo et al..  2017.  Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.. Sci Rep. 7(1):900.
E
Mahar I, MacIsaac A, Kim JJunghan, Qiang C, Davoli MAntonietta, Turecki G, Mechawar N.  2016.  Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis.. Sci Rep. 6:30467.
Nagy C, Maheu M, Lopez JPablo, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G.  2015.  Effects of postmortem interval on biomolecule integrity in the brain.. J Neuropathol Exp Neurol. 74(5):459-69.
Torres-Platas SG, Cruceanu C, Chen GGang, Turecki G, Mechawar N.  2014.  Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides.. Brain Behav Immun. 42:50-9.
Tanti A, Lutz P-E, Kim J, O'Leary L, Théroux J-F, Turecki G, Mechawar N.  2019.  Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides.. Neuropsychopharmacology. 44(12):2099-2111.
Huh CYL, Amilhon B, Ferguson KA, Manseau F, Torres-Platas SG, Peach JP, Scodras S, Mechawar N, Skinner FK, Williams S.  2016.  Excitatory Inputs Determine Phase-Locking Strength and Spike-Timing of CA1 Stratum Oriens/Alveus Parvalbumin and Somatostatin Interneurons during Intrinsically Generated Hippocampal Theta Rhythm.. J Neurosci. 36(25):6605-22.
F
Rocco BR, Oh H, Shukla R, Mechawar N, Sibille E.  2017.  Fluorescence-based cell-specific detection for laser-capture microdissection in human brain.. Sci Rep. 7(1):14213.
Maussion G, Yang J, Suderman M, Diallo A, Nagy C, Arnovitz M, Mechawar N, Turecki G.  2014.  Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide.. Epigenetics. 9(8):1061-70.
G
Torres-Platas SG, Nagy C, Wakid M, Turecki G, Mechawar N.  2016.  Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides.. Mol Psychiatry. 21(4):509-15.
Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G.  2016.  Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval.. Front Genet. 7:120.
H
Bouvier DS, Jones EV, Quesseveur G, Davoli MAntonietta, Ferreira TA, Quirion R, Mechawar N, Murai KK.  2016.  High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease.. Sci Rep. 6:24544.
I
Maheu ME, Devorak J, Freibauer A, Davoli MAntonietta, Turecki G, Mechawar N.  2015.  Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides.. Front Neuroanat. 9:74.

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