Publications

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Lin M-S, Xiong W-C, Li S-J, Gong Z, Cao X, Kuang X-J, Zhang Y, Gao T-M, Mechawar N, Liu C et al..  2017.  α2-glycine receptors modulate adult hippocampal neurogenesis and spatial memory.. Dev Neurobiol. 77(12):1430-1441.
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O'Leary LAnuj, Belliveau C, Davoli MAntonietta, Ma JChristophe, Tanti A, Turecki G, Mechawar N.  2021.  Widespread Decrease of Cerebral Vimentin-Immunoreactive Astrocytes in Depressed Suicides.. Front Psychiatry. 12:640963.
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Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A et al..  2018.  Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.. Nat Commun. 9(1):2459.
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Mahar I, Bambico FRodriguez, Mechawar N, Nobrega JN.  2014.  Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects.. Neurosci Biobehav Rev. 38:173-92.
Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Théroux J-F, Moquin L et al..  2020.  Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.. Stem Cells Transl Med. 9(6):697-712.
Nagy C, Maitra M, Tanti A, Suderman M, Théroux J-F, Davoli MAntonietta, Perlman K, Yerko V, Wang YChang, Tripathy SJ et al..  2020.  Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons.. Nat Neurosci. 23(6):771-781.
Labonte B, Engmann O, Purushothaman I, Ménard C, Wang J, Tan C, Scarpa JR, Moy G, Loh Y-HE, Cahill M et al..  2017.  Sex-specific transcriptional signatures in human depression.. Nat Med. 23(9):1102-1111.
Kaul D, Smith CC, Stevens J, Fröhlich AS, Binder EB, Mechawar N, Schwab SG, Matosin N.  2020.  Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders.. Neurobiol Stress. 13:100270.
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Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu AP, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM et al..  2019.  Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration.. Sci Rep. 9(1):7850.
Pabba M, Scifo E, Kapadia F, Nikolova YS, Ma T, Mechawar N, Tseng GC, Sibille E.  2017.  Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging.. Neurobiol Aging. 58:180-190.
Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F et al..  2016.  Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons.. Nat Neurosci. 19(4):560-3.
Nagy C, Torres-Platas SG, Mechawar N, Turecki G.  2016.  Repression of Astrocytic Connexins in Cortical and Subcortical Brain Regions and Prefrontal Enrichment of H3K9me3 in Depression and Suicide.. Int J Neuropsychopharmacol.
Lopez JPablo, Fiori LM, Gross JA, Labonte B, Yerko V, Mechawar N, Turecki G.  2014.  Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers.. Int J Neuropsychopharmacol. 17(1):23-32.
Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM et al..  2018.  Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor.. Neuroimage. 176:226-238.
Albuquerque MS, Mahar I, Davoli MAntonietta, Chabot J-G, Mechawar N, Quirion R, Krantic S.  2015.  Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease.. Front Aging Neurosci. 7:30.
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Trépanier MO, Hopperton KE, Mizrahi R, Mechawar N, Bazinet RP.  2016.  Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review.. Mol Psychiatry. 21(8):1009-26.
Mahar I, Albuquerque MSilva, Mondragon-Rodriguez S, Cavanagh C, Davoli MAntonietta, Chabot J-G, Williams S, Mechawar N, Quirion R, Krantic S.  2016.  Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer's Disease.. Front Aging Neurosci. 8:327.
Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy J-P, Aliaga A, Kostikov A, Maclaren DAA, Clark SD, Bedard M-A.  2014.  PET imaging with [¹⁸F]fluoroethoxybenzovesamicol ([¹⁸F]FEOBV) following selective lesion of cholinergic pedunculopontine tegmental neurons in rat.. Nucl Med Biol. 41(1):96-101.
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Almeida D, Fiori LM, Chen GG, Aouabed Z, Lutz P-E, Zhang T-Y, Mechawar N, Meaney MJ, Turecki G.  2022.  Oxytocin receptor expression and epigenetic regulation in the anterior cingulate cortex of individuals with a history of severe childhood abuse.. Psychoneuroendocrinology. 136:105600.
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Lutz P-E, Chay M-A, Pacis A, Chen GG, Aouabed Z, Maffioletti E, Théroux J-F, Grenier J-C, Yang J, Aguirre M et al..  2021.  Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation.. Nat Commun. 12(1):1132.
Hökfelt T, Barde S, Xu Z-QDavid, Kuteeva E, Rüegg J, Le Maitre E, Risling M, Kehr J, Ihnatko R, Theodorsson E et al..  2018.  Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness.. Front Neural Circuits. 12:106.
Mechawar N, Savitz J.  2016.  Neuropathology of mood disorders: do we see the stigmata of inflammation? Transl Psychiatry. 6(11):e946.
Saeedi S, Nagy C, Ibrahim P, Théroux J-F, Wakid M, Fiori LM, Yang J, Rotzinger S, Foster JA, Mechawar N et al..  2021.  Neuron-derived extracellular vesicles enriched from plasma show altered size and miRNA cargo as a function of antidepressant drug response.. Mol Psychiatry.
Kelaï S, Ramoz N, Moalic J-M, Noble F, Mechawar N, Imbeaud S, Turecki G, Simonneau M, Gorwood P, Maussion G.  2017.  Netrin G1: its downregulation in the nucleus accumbens of cocaine-conditioned mice and genetic association in human cocaine dependence.. Addict Biol.
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Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Théroux J-F, Jefri M, Tanti A, Wu H, Kolobova I et al..  2019.  Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.. Am J Hum Genet. 104(5):815-834.

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