Publications

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Journal Article
Barde S, Rüegg J, Prud'homme J, Ekström TJ, Palkovits M, Turecki G, Bagdy G, Ihnatko R, Theodorsson E, Juhasz G et al..  2016.  Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide.. Proc Natl Acad Sci U S A. 113(52):E8472-E8481.
Silva PNatalia, Furuya TKatsue, Braga ILacerda, Rasmussen LTrevizani, Labio RWillian, Bertolucci PHenrique, Chen ESuchi, Turecki G, Mechawar N, Payão SLuiz et al..  2014.  Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients.. J Alzheimers Dis. 38(1):165-70.
Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G.  2015.  Astrocytic abnormalities and global DNA methylation patterns in depression and suicide.. Mol Psychiatry. 20(3):320-8.
Devorak J, Torres-Platas SGabriela, Davoli MAntonietta, Prud'homme J, Turecki G, Mechawar N.  2015.  Cellular and Molecular Inflammatory Profile of the Choroid Plexus in Depression and Suicide.. Front Psychiatry. 6:138.
Lutz P-E, Zhou Y, Labbe A, Mechawar N, Turecki G.  2015.  Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicides.. Eur Neuropsychopharmacol. 25(11):2008-14.
Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy J-P, Clark SD, Aghourian M, Bedard M-A.  2015.  Deficit in sustained attention following selective cholinergic lesion of the pedunculopontine tegmental nucleus in rat, as measured with both post-mortem immunocytochemistry and in vivo PET imaging with [¹⁸F]fluoroethoxybenzovesamicol.. Behav Brain Res. 278:107-14.
Vigneault E, Poirel O, Riad M, Prud'homme J, Dumas S, Turecki G, Fasano C, Mechawar N, Mestikawy SEl.  2015.  Distribution of vesicular glutamate transporters in the human brain.. Front Neuroanat. 9:23.
Han S, Yang SHyun, Kim JYong, Mo S, Yang E, Song KMyung, Ham B-J, Mechawar N, Turecki G, Lee HWoo et al..  2017.  Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.. Sci Rep. 7(1):900.
Mahar I, MacIsaac A, Kim JJunghan, Qiang C, Davoli MAntonietta, Turecki G, Mechawar N.  2016.  Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis.. Sci Rep. 6:30467.
Nagy C, Maheu M, Lopez JPablo, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G.  2015.  Effects of postmortem interval on biomolecule integrity in the brain.. J Neuropathol Exp Neurol. 74(5):459-69.
Torres-Platas SG, Cruceanu C, Chen GGang, Turecki G, Mechawar N.  2014.  Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides.. Brain Behav Immun. 42:50-9.
Huh CYL, Amilhon B, Ferguson KA, Manseau F, Torres-Platas SG, Peach JP, Scodras S, Mechawar N, Skinner FK, Williams S.  2016.  Excitatory Inputs Determine Phase-Locking Strength and Spike-Timing of CA1 Stratum Oriens/Alveus Parvalbumin and Somatostatin Interneurons during Intrinsically Generated Hippocampal Theta Rhythm.. J Neurosci. 36(25):6605-22.
Maussion G, Yang J, Suderman M, Diallo A, Nagy C, Arnovitz M, Mechawar N, Turecki G.  2014.  Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide.. Epigenetics. 9(8):1061-70.
Torres-Platas SG, Nagy C, Wakid M, Turecki G, Mechawar N.  2016.  Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides.. Mol Psychiatry. 21(4):509-15.
Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G.  2016.  Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval.. Front Genet. 7:120.
Bouvier DS, Jones EV, Quesseveur G, Davoli MAntonietta, Ferreira TA, Quirion R, Mechawar N, Murai KK.  2016.  High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease.. Sci Rep. 6:24544.
Maheu ME, Devorak J, Freibauer A, Davoli MAntonietta, Turecki G, Mechawar N.  2015.  Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides.. Front Neuroanat. 9:74.
Chen GG, Gross JA, Lutz P-E, Vaillancourt K, Maussion G, Bramoulle A, Théroux J-F, Gardini ES, Ehlert U, Bourret G et al..  2017.  Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine.. BMC Genomics. 18(1):96.
Pidsley R, Viana J, Hannon E, Spiers H, Troakes C, Al-Saraj S, Mechawar N, Turecki G, Schalkwyk LC, Bray NJ et al..  2014.  Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia.. Genome Biol. 15(10):483.
Maheu M, Lopez JP, Crapper L, Davoli MA, Turecki G, Mechawar N.  2015.  MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression.. Transl Psychiatry. 5:e511.
Lopez JPablo, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C et al..  2017.  MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.. Nat Commun. 8:15497.
Lopez JPablo, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, Maussion G, Yang JP, Yerko V, Vigneault E et al..  2014.  miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment.. Nat Med. 20(7):764-8.
Torres-Platas SG, Comeau S, Rachalski A, Dal Bo G, Cruceanu C, Turecki G, Giros B, Mechawar N.  2014.  Morphometric characterization of microglial phenotypes in human cerebral cortex.. J Neuroinflammation. 11:12.
Kelaï S, Ramoz N, Moalic J-M, Noble F, Mechawar N, Imbeaud S, Turecki G, Simonneau M, Gorwood P, Maussion G.  2017.  Netrin G1: its downregulation in the nucleus accumbens of cocaine-conditioned mice and genetic association in human cocaine dependence.. Addict Biol.
Mechawar N, Savitz J.  2016.  Neuropathology of mood disorders: do we see the stigmata of inflammation? Transl Psychiatry. 6(11):e946.

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