Publications

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Journal Article
Mahar I, Bambico FRodriguez, Mechawar N, Nobrega JN.  2014.  Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects.. Neurosci Biobehav Rev. 38:173-92.
Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F et al..  2016.  Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons.. Nat Neurosci. 19(4):560-3.
Nagy C, Torres-Platas SG, Mechawar N, Turecki G.  2016.  Repression of Astrocytic Connexins in Cortical and Subcortical Brain Regions and Prefrontal Enrichment of H3K9me3 in Depression and Suicide.. Int J Neuropsychopharmacol.
Lopez JPablo, Fiori LM, Gross JA, Labonte B, Yerko V, Mechawar N, Turecki G.  2014.  Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers.. Int J Neuropsychopharmacol. 17(1):23-32.
Albuquerque MS, Mahar I, Davoli MAntonietta, Chabot J-G, Mechawar N, Quirion R, Krantic S.  2015.  Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease.. Front Aging Neurosci. 7:30.
Trépanier MO, Hopperton KE, Mizrahi R, Mechawar N, Bazinet RP.  2016.  Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review.. Mol Psychiatry. 21(8):1009-26.
Mahar I, Albuquerque MSilva, Mondragon-Rodriguez S, Cavanagh C, Davoli MAntonietta, Chabot J-G, Williams S, Mechawar N, Quirion R, Krantic S.  2016.  Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer's Disease.. Front Aging Neurosci. 8:327.
Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy J-P, Aliaga A, Kostikov A, Maclaren DAA, Clark SD, Bedard M-A.  2014.  PET imaging with [¹⁸F]fluoroethoxybenzovesamicol ([¹⁸F]FEOBV) following selective lesion of cholinergic pedunculopontine tegmental neurons in rat.. Nucl Med Biol. 41(1):96-101.
Mechawar N, Savitz J.  2016.  Neuropathology of mood disorders: do we see the stigmata of inflammation? Transl Psychiatry. 6(11):e946.
Kelaï S, Ramoz N, Moalic J-M, Noble F, Mechawar N, Imbeaud S, Turecki G, Simonneau M, Gorwood P, Maussion G.  2017.  Netrin G1: its downregulation in the nucleus accumbens of cocaine-conditioned mice and genetic association in human cocaine dependence.. Addict Biol.
Torres-Platas SG, Comeau S, Rachalski A, Dal Bo G, Cruceanu C, Turecki G, Giros B, Mechawar N.  2014.  Morphometric characterization of microglial phenotypes in human cerebral cortex.. J Neuroinflammation. 11:12.
Lopez JPablo, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, Maussion G, Yang JP, Yerko V, Vigneault E et al..  2014.  miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment.. Nat Med. 20(7):764-8.
Lopez JPablo, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C et al..  2017.  MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.. Nat Commun. 8:15497.
Maheu M, Lopez JP, Crapper L, Davoli MA, Turecki G, Mechawar N.  2015.  MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression.. Transl Psychiatry. 5:e511.
Pidsley R, Viana J, Hannon E, Spiers H, Troakes C, Al-Saraj S, Mechawar N, Turecki G, Schalkwyk LC, Bray NJ et al..  2014.  Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia.. Genome Biol. 15(10):483.
Chen GG, Gross JA, Lutz P-E, Vaillancourt K, Maussion G, Bramoulle A, Théroux J-F, Gardini ES, Ehlert U, Bourret G et al..  2017.  Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine.. BMC Genomics. 18(1):96.
Maheu ME, Devorak J, Freibauer A, Davoli MAntonietta, Turecki G, Mechawar N.  2015.  Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides.. Front Neuroanat. 9:74.
Bouvier DS, Jones EV, Quesseveur G, Davoli MAntonietta, Ferreira TA, Quirion R, Mechawar N, Murai KK.  2016.  High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease.. Sci Rep. 6:24544.
Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G.  2016.  Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval.. Front Genet. 7:120.
Torres-Platas SG, Nagy C, Wakid M, Turecki G, Mechawar N.  2016.  Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides.. Mol Psychiatry. 21(4):509-15.
Maussion G, Yang J, Suderman M, Diallo A, Nagy C, Arnovitz M, Mechawar N, Turecki G.  2014.  Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide.. Epigenetics. 9(8):1061-70.
Huh CYL, Amilhon B, Ferguson KA, Manseau F, Torres-Platas SG, Peach JP, Scodras S, Mechawar N, Skinner FK, Williams S.  2016.  Excitatory Inputs Determine Phase-Locking Strength and Spike-Timing of CA1 Stratum Oriens/Alveus Parvalbumin and Somatostatin Interneurons during Intrinsically Generated Hippocampal Theta Rhythm.. J Neurosci. 36(25):6605-22.
Torres-Platas SG, Cruceanu C, Chen GGang, Turecki G, Mechawar N.  2014.  Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides.. Brain Behav Immun. 42:50-9.
Nagy C, Maheu M, Lopez JPablo, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G.  2015.  Effects of postmortem interval on biomolecule integrity in the brain.. J Neuropathol Exp Neurol. 74(5):459-69.
Mahar I, MacIsaac A, Kim JJunghan, Qiang C, Davoli MAntonietta, Turecki G, Mechawar N.  2016.  Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis.. Sci Rep. 6:30467.

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