Publications

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2021
Gonneaud J, Baria AT, Binette APichet, Gordon BA, Chhatwal JP, Cruchaga C, Jucker M, Levin J, Salloway S, Farlow M et al..  2021.  Accelerated functional brain aging in pre-clinical familial Alzheimer's disease.. Nat Commun. 12(1):5346.
Picard C, Nilsson N, Labonte A, Auld D, Rosa-Neto P, Ashton NJ, Zetterberg H, Blennow K, Breitner JCS, Villeneuve S et al..  2021.  Apolipoprotein B is a novel marker for early tau pathology in Alzheimer's disease.. Alzheimers Dement.
Binette APichet, Theaud G, Rheault F, Roy M, D Collins L, Levin J, Mori H, Lee JHong, Farlow MRhys, Schofield P et al..  2021.  Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease.. Elife. 10
Peters R, Breitner JCS, James S, Jicha GA, Meyer P-F, Richards M, A Smith D, Yassine HN, Abner E, Hainsworth AH et al..  2021.  Dementia risk reduction: why haven't the pharmacological risk reduction trials worked? An in-depth exploration of seven established risk factors. Alzheimers Dement (N Y). 7(1):e12202.
Tremblay-Mercier J, Madjar C, Das S, Binette APichet, Dyke SOM, Etienne P, Lafaille-Magnan M-E, Remz J, Bellec P, D Collins L et al..  2021.  Open science datasets from PREVENT-AD, a longitudinal cohort of pre-symptomatic Alzheimer's disease.. Neuroimage Clin. 31:102733.
Köbe T, Binette APichet, Vogel JW, Meyer P-F, Breitner JCS, Poirier J, Villeneuve S.  2021.  Vascular risk factors are associated with a decline in resting-state functional connectivity in cognitively unimpaired individuals at risk for Alzheimer's disease: Vascular risk factors and functional connectivity changes.. Neuroimage. 231:117832.
2020
Binette APichet, Vachon-Presseau E, Morris J, Bateman R, Benzinger T, D Collins L, Poirier J, Breitner JCS, Villeneuve S.  2020.  Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease.. Biol Psychiatry.
Rabipour S, Rajagopal S, Yu E, Pasvanis S, Lafaille-Magnan M-E, Breitner JCS, Maria Rajah N.  2020.  APOE4 Status is Related to Differences in Memory-Related Brain Function in Asymptomatic Older Adults with Family History of Alzheimer's Disease: Baseline Analysis of the PREVENT-AD Task Functional MRI Dataset.. J Alzheimers Dis. 76(1):97-119.
Gonneaud J, Bedetti C, Binette APichet, Benzinger TLS, Morris JC, Bateman RJ, Poirier J, Breitner JCS, Villeneuve S.  2020.  Association of education with Aβ burden in preclinical familial and sporadic Alzheimer disease.. Neurology. 95(11):e1554-e1564.
Binette APichet, Gonneaud J, Vogel JW, La Joie R, Rosa-Neto P, D Collins L, Poirier J, Breitner JCS, Villeneuve S, Vachon-Presseau E.  2020.  Morphometric network differences in ageing versus Alzheimer's disease dementia.. Brain. 143(2):635-649.
2019
Miron J, Picard C, Labonte A, Auld D, Breitner JCS, Poirier J.  2019.  Association of PPP2R1A with Alzheimer's disease and specific cognitive domains.. Neurobiol Aging. 81:234-243.
Miron J, Picard C, Lafaille-Magnan M-E, Savard M, Labonte A, Breitner JCS, Rosa-Neto P, Auld D, Poirier J.  2019.  Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation.. Alzheimers Dement. 15(7):951-960.
Liebsch F, Kulic L, Teunissen C, Shobo A, Ulku I, Engelschalt V, Hancock MA, van der Flier WM, Kunach P, Rosa-Neto P et al..  2019.  Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.. Nat Commun. 10(1):2240.
Tam A, Dansereau C, Iturria-Medina Y, Urchs S, Orban P, Sharmarke H, Breitner JCS, Bellec P.  2019.  A highly predictive signature of cognition and brain atrophy for progression to Alzheimer's dementia.. Gigascience. 8(5)
Meyer P-F, Savard M, Poirier J, Morgan D, Breitner JCS.  2019.  Hypothesis: cerebrospinal fluid protein markers suggest a pathway toward symptomatic resilience to AD pathology.. Alzheimers Dement. 15(9):1160-1171.
Meyer P-F, Tremblay-Mercier J, Leoutsakos J, Madjar C, Lafaille-Maignan M-É, Savard M, Rosa-Neto P, Poirier J, Etienne P, Breitner JCS.  2019.  INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease.. Neurology. 92(18):e2070-e2080.
Tullo S, Patel R, Devenyi GA, Salaciak A, Bedford SA, Farzin S, Wlodarski N, Tardif CL, Breitner JCS, Chakravarty MM.  2019.  MR-based age-related effects on the striatum, globus pallidus, and thalamus in healthy individuals across the adult lifespan.. Hum Brain Mapp.
Meyer P-F, Labonte A, Rosa-Neto P, Poirier J, Breitner JCS.  2019.  No apparent effect of naproxen on CSF markers of innate immune activation.. Ann Clin Transl Neurol. 6(6):1127-1133.
2018
Picard C, Julien C, Frappier J, Miron J, Théroux L, Dea D, Breitner JCS, Poirier J.  2018.  Alterations in cholesterol metabolism-related genes in sporadic Alzheimer's disease.. Neurobiol Aging. 66:180.e1-180.e9.
Meyer P-F, Savard M, Poirier J, Labonte A, Rosa-Neto P, Weitz TM, Town T, Breitner JCS.  2018.  Bi-directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer's Disease Pathogenesis.. J Alzheimers Dis. 63(2):577-590.
Vogel JW, Vachon-Presseau E, Binette APichet, Tam A, Orban P, La Joie R, Savard M, Picard C, Poirier J, Bellec P et al..  2018.  Brain properties predict proximity to symptom onset in sporadic Alzheimer's disease.. Brain. 141(6):1871-1883.
Konishi K, Joober R, Poirier J, MacDonald K, Chakravarty MM, Patel R, Breitner JCS, Bohbot VD.  2018.  Healthy versus Entorhinal Cortical Atrophy Identification in Asymptomatic APOE4 Carriers at Risk for Alzheimer's Disease.. J Alzheimers Dis. 61(4):1493-1507.
Villeneuve S, Vogel JW, Gonneaud J, Binette APichet, Rosa-Neto P, Gauthier S, Bateman RJ, Fagan AM, Morris JC, Benzinger TLS et al..  2018.  Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease.. JAMA Neurol.
Tardif CL, Devenyi GA, Amaral RSC, Pelleieux S, Poirier J, Rosa-Neto P, Breitner JCS, Chakravarty MM.  2018.  Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease.. Hum Brain Mapp. 39(2):971-984.
Verfaillie SCJ, Binette APichet, Vachon-Presseau E, Tabrizi S, Savard M, Bellec P, Ossenkoppele R, Scheltens P, van der Flier WM, Breitner JCS et al..  2018.  Subjective Cognitive Decline Is Associated With Altered Default Mode Network Connectivity in Individuals With a Family History of Alzheimer's Disease.. Biol Psychiatry Cogn Neurosci Neuroimaging. 3(5):463-472.

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