Publications

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Journal Article
Mathotaarachchi S, Wang S, Shin M, Pascoal TA, Benedet AL, Kang MSu, Beaudry T, Fonov VS, Gauthier S, Labbe A et al..  2016.  VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis.. Front Neuroinform. 10:20.
Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang M-S, Gauthier S, Rouleau GA, Poirier J et al..  2018.   variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.. Neurol Genet. 4(1):e216.
Pascoal TA, Mathotaarachchi S, Shin M, Benedet AL, Mohades S, Wang S, Beaudry T, Kang MSu, Soucy J-P, Labbe A et al..  2017.  Synergistic interaction between amyloid and tau predicts the progression to dementia.. Alzheimers Dement. 13(6):644-653.
Ng KPin, Richard-Devantoy S, Bertrand J-A, Jiang L, Pascoal TA, Mathotaarachchi S, Therriault J, Yatawara C, Kandiah N, Greenwood CMT et al..  2020.  Suicidal ideation is common in autosomal dominant Alzheimer's disease at-risk persons.. Int J Geriatr Psychiatry. 35(1):60-68.
Schilling LPorcello, Pascoal TA, Zimmer ER, Mathotaarachchi S, Shin M, Rieder CRoberto de, Gauthier S, Palmini A, Rosa-Neto P.  2018.  Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia.. Mol Neurobiol.
Ng KPin, Therriault J, Kang MSu, Struyfs H, Pascoal TA, Mathotaarachchi S, Shin M, Benedet AL, Massarweh G, Soucy J-P et al..  2019.  Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [F]THK5351 uptake in progressive supranuclear palsy.. Neuroimage Clin. 24:102091.
Pascoal TA, Benedet AL, Ashton NJ, Kang MSu, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK et al..  2021.  Publisher Correction: Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(11):2048-2049.
Ba M, Li X, Ng KPin, Pascoal TA, Mathotaarachchi S, Rosa-Neto P, Gauthier S.  2017.  The prevalence and biomarkers' characteristic of rapidly progressive Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database.. Alzheimers Dement (N Y). 3(1):107-113.
Kang MSu, Shin M, Ottoy J, Aliaga AAliaga, Mathotaarachchi S, Quispialaya K, Pascoal TA, D Collins L, Chakravarty MM, Mathieu A et al..  2021.  Preclinical longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease therapeutic.. J Cereb Blood Flow Metab. :271678X211035625.
Hadoux X, Hui F, Lim JKH, Masters CL, Pébay A, Chevalier S, Ha J, Loi S, Fowler CJ, Rowe C et al..  2019.  Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease.. Nat Commun. 10(1):4227.
Ng KPin, Pascoal TA, Mathotaarachchi S, Chung C-O, Benedet AL, Shin M, Kang MSu, Li X, Ba M, Kandiah N et al..  2017.  Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.. Neurology. 88(19):1814-1821.
Ng KPin, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MSu, Shin M, Guiot M-C, Guo Q, Harada R, Comley RA et al..  2017.  Monoamine oxidase B inhibitor, selegiline, reduces (18)F-THK5351 uptake in the human brain.. Alzheimers Res Ther. 9(1):25.
Pascoal TA, Benedet AL, Ashton NJ, Kang MSu, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK et al..  2021.  Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(9):1592-1599.
Pascoal TA, Benedet AL, Tudorascu DL, Therriault J, Mathotaarachchi S, Savard M, Lussier FZ, Tissot C, Chamoun M, Kang MSu et al..  2021.  Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.. Brain. 144(11):3517-3528.
DuBois JM, Mathotaarachchi S, Rousset OG, Sziklas V, Sepulcre J, Guiot M-C, Hall JA, Massarweh G, Soucy J-P, Rosa-Neto P et al..  2021.  Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia.. Neuroimage Clin. 29:102552.
Wang Y-TT, Pascoal TA, Therriault J, Kang MSu, Benedet AL, Savard M, Tissot C, Lussier FZ, Arias JFernandez, Mathotaarachchi S et al..  2021.  Interactive rather than independent effect of and sex potentiates tau deposition in women.. Brain Commun. 3(2):fcab126.
Pascoal TA, Shin M, Kang MSu, Chamoun M, Chartrand D, Mathotaarachchi S, Bennacef I, Therriault J, Ng KPin, Hopewell R et al..  2018.  In vivo quantification of neurofibrillary tangles with [F]MK-6240.. Alzheimers Res Ther. 10(1):74.
Mathotaarachchi S, Pascoal TA, Shin M, Benedet AL, Kang MSu, Beaudry T, Fonov VS, Gauthier S, Rosa-Neto P.  2017.  Identifying incipient dementia individuals using machine learning and amyloid imaging.. Neurobiol Aging. 59:80-90.
Benedet AL, Labbe A, Lemay P, Zimmer ER, Pascoal TA, Leuzy A, Mathotaarachchi S, Mohades S, Shin M, Dionne-Laporte A et al..  2015.  Epistasis analysis links immune cascades and cerebral amyloidosis.. J Neuroinflammation. 12:227.
Jiang L, Oualkacha K, Didelez V, Ciampi A, Rosa-Neto P, Benedet AL, Mathotaarachchi S, Richards JBrent, Greenwood CMT.  2019.  Constrained instruments and their application to Mendelian randomization with pleiotropy.. Genet Epidemiol.
Li X, Ba M, Ng KPin, Mathotaarachchi S, Pascoal TA, Rosa-Neto P, Gauthier S.  2018.  Characterizing biomarker features of cognitively normal individuals with ventriculomegaly.. Alzheimers Dement (Amst). 10:12-21.
Gauthier S, Ng KPin, Pascoal TA, Mathotaarachchi S, Chung C-O, Benedetti AL, Shin M, Kang MSu, Li X, Ba M et al..  2017.  Author response: Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.. Neurology. 89(18):1931.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Savard M, Chamoun M, Thomas É, Kang MSu, Lussier F, Tissot C et al..  2020.  APOEε4 potentiates the relationship between amyloid-β and tau pathologies.. Mol Psychiatry.
Therriault J, Ng KPin, Pascoal TA, Mathotaarachchi S, Kang MSu, Struyfs H, Shin M, Benedet AL, Walpola IC, Nair V et al..  2018.  Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.. Neurology. 90(11):e932-e939.
Therriault J, Pascoal TA, Sefranek M, Mathotaarachchi S, Benedet AL, Chamoun M, Lussier FZ, Tissot C, Bellaver B, Lukasewicz PS et al..  2021.  Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia.. Ann Clin Transl Neurol. 8(10):2083-2092.

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