Publications

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2021
Levy JP, Bezgin G, Savard M, Pascoal TA, Finger E, Laforce R, Sonnen JA, Soucy J-P, Gauthier S, Rosa-Neto P et al..  2021.  18F-MK-6240 tau-PET in genetic frontotemporal dementia.. Brain.
Therriault J, Pascoal TA, Sefranek M, Mathotaarachchi S, Benedet AL, Chamoun M, Lussier FZ, Tissot C, Bellaver B, Lukasewicz PS et al..  2021.  Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia.. Ann Clin Transl Neurol. 8(10):2083-2092.
Tissot C, Therriault J, Pascoal TA, Chamoun M, Lussier FZ, Savard M, Mathotaarachchi SS, Benedet AL, Thomas EM, Parsons M et al..  2021.  Association between regional tau pathology and neuropsychiatric symptoms in aging and dementia due to Alzheimer's disease.. Alzheimers Dement (N Y). 7(1):e12154.
Therriault J, Pascoal TA, Benedet AL, Tissot C, Savard M, Chamoun M, Lussier F, Kang MSu, Berzgin G, Wang T et al..  2021.  Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, ε4, and Cognitive Impairment.. Neurology. 96(7):e975-e985.
Wang Y-TT, Pascoal TA, Therriault J, Kang MSu, Benedet AL, Savard M, Tissot C, Lussier FZ, Arias JFernandez, Mathotaarachchi S et al..  2021.  Interactive rather than independent effect of and sex potentiates tau deposition in women.. Brain Commun. 3(2):fcab126.
Pascoal TA, Benedet AL, Tudorascu DL, Therriault J, Mathotaarachchi S, Savard M, Lussier FZ, Tissot C, Chamoun M, Kang MSu et al..  2021.  Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.. Brain. 144(11):3517-3528.
Pascoal TA, Benedet AL, Ashton NJ, Kang MSu, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK et al..  2021.  Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(9):1592-1599.
Tissot C, Benedet AL, Therriault J, Pascoal TA, Lussier FZ, Saha-Chaudhuri P, Chamoun M, Savard M, Mathotaarachchi SS, Bezgin G et al..  2021.  Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer's disease.. Alzheimers Res Ther. 13(1):69.
Kang MSu, Shin M, Ottoy J, Aliaga AAliaga, Mathotaarachchi S, Quispialaya K, Pascoal TA, D Collins L, Chakravarty MM, Mathieu A et al..  2021.  Preclinical longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease therapeutic.. J Cereb Blood Flow Metab. :271678X211035625.
Silva NMLyra E, Gonçalves RA, Pascoal TA, Lima-Filho RAS, Resende Ede Paula F, Vieira ELM, Teixeira AL, de Souza LC, Peny JA, Fortuna JTS et al..  2021.  Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease.. Transl Psychiatry. 11(1):251.
Pascoal TA, Benedet AL, Ashton NJ, Kang MSu, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK et al..  2021.  Publisher Correction: Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(11):2048-2049.
Povala G, Bellaver B, De Bastiani MAntônio, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM et al..  2021.  Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.. Cell Biosci. 11(1):204.
2020
Pascoal TA, Therriault J, Benedet AL, Savard M, Lussier FZ, Chamoun M, Tissot C, Qureshi MNaveed Iqb, Kang MSu, Mathotaarachchi S et al..  2020.  18F-MK-6240 PET for early and late detection of neurofibrillary tangles.. Brain. 143(9):2818-2830.
Kang MSu, Aliaga AAliaga, Shin M, Mathotaarachchi S, Benedet AL, Pascoal TA, Therriault J, Chamoun M, Savard M, Devenyi GA et al..  2020.  Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer's disease.. Mol Psychiatry.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Savard M, Chamoun M, Thomas É, Kang MSu, Lussier F, Tissot C et al..  2020.  APOEε4 potentiates the relationship between amyloid-β and tau pathologies.. Mol Psychiatry.
Favier M, Janickova H, Justo D, Kljakic O, Runtz L, Natsheh JY, Pascoal TA, Germann J, Gallino D, Kang J-I et al..  2020.  Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating.. J Clin Invest. 130(12):6616-6630.
Ng KPin, Richard-Devantoy S, Bertrand J-A, Jiang L, Pascoal TA, Mathotaarachchi S, Therriault J, Yatawara C, Kandiah N, Greenwood CMT et al..  2020.  Suicidal ideation is common in autosomal dominant Alzheimer's disease at-risk persons.. Int J Geriatr Psychiatry. 35(1):60-68.
Therriault J, Pascoal TA, Savard M, Benedet AL, Chamoun M, Tissot C, Lussier F, Kang MSu, Thomas É, Terada T et al..  2020.  Topographical distribution of amyloid-β, tau and atrophy in behavioral / dysexecutive AD patients.. Neurology.

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