Publications

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Author Title [ Type(Asc)] Year
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Journal Article
Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Théroux J-F, Moquin L et al..  2020.  Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.. Stem Cells Transl Med. 9(6):697-712.
Nagy C, Maitra M, Tanti A, Suderman M, Théroux J-F, Davoli MAntonietta, Perlman K, Yerko V, Wang YChang, Tripathy SJ et al..  2020.  Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons.. Nat Neurosci. 23(6):771-781.
Lutz P-E, Chay M-A, Pacis A, Chen GG, Aouabed Z, Maffioletti E, Théroux J-F, Grenier J-C, Yang J, Aguirre M et al..  2021.  Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation.. Nat Commun. 12(1):1132.
W Farmer T, Abrahamsson T, Chierzi S, Lui C, Zaelzer C, Jones EV, Bally BPonroy, Chen GG, Théroux J-F, Peng J et al..  2016.  Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling.. Science. 351(6275):849-54.
Saeedi S, Nagy C, Ibrahim P, Théroux J-F, Wakid M, Fiori LM, Yang J, Rotzinger S, Foster JA, Mechawar N et al..  2021.  Neuron-derived extracellular vesicles enriched from plasma show altered size and miRNA cargo as a function of antidepressant drug response.. Mol Psychiatry.
Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Théroux J-F, Jefri M, Tanti A, Wu H, Kolobova I et al..  2019.  Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.. Am J Hum Genet. 104(5):815-834.
Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Théroux J-F, Jefri M, Tanti A, Wu H, Kolobova I et al..  2019.  Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons. The American Journal of Human Genetics.
Fiori LM, Kos A, Lin R, Théroux J-F, Lopez JPablo, Kühne C, Eggert C, Holzapfel M, Huettl R-E, Mechawar N et al..  2020.  miR-323a regulates ERBB4 and is involved in depression.. Mol Psychiatry.
Vaillancourt K, Chen GG, Fiori L, Maussion G, Yerko V, Théroux J-F, Ernst C, Labonte B, Calipari E, Nestler EJ et al..  2021.  Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum.. iScience. 24(10):103169.
Chen GG, Gross JA, Lutz P-E, Vaillancourt K, Maussion G, Bramoulle A, Théroux J-F, Gardini ES, Ehlert U, Bourret G et al..  2017.  Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine.. BMC Genomics. 18(1):96.
Maussion G, Diallo AB, Gigek CO, Chen ES, Crapper L, Théroux J-F, Chen GG, Vasuta C, Ernst C.  2015.  Investigation of genes important in neurodevelopment disorders in adult human brain.. Hum Genet. 134(10):1037-53.
Ju C, Fiori LM, Belzeaux R, Théroux J-F, Chen GGang, Aouabed Z, Blier P, Farzan F, Frey BN, Giacobbe P et al..  2019.  Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants.. Transl Psychiatry. 9(1):254.
Belzeaux R, Gorgievski V, Fiori LM, Lopez JPablo, Grenier J, Lin R, Nagy C, Ibrahim EChérif, Gascon E, Courtet P et al..  2020.  GPR56/ADGRG1 is associated with response to antidepressant treatment.. Nat Commun. 11(1):1635.
Maitra M, Nagy C, Chawla A, Wang YChang, Nascimento C, Suderman M, Théroux J-F, Mechawar N, Ragoussis J, Turecki G.  2021.  Extraction of nuclei from archived postmortem tissues for single-nucleus sequencing applications.. Nat Protoc. 16(6):2788-2801.
Tanti A, Lutz P-E, Kim J, O'Leary L, Théroux J-F, Turecki G, Mechawar N.  2019.  Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides.. Neuropsychopharmacology. 44(12):2099-2111.
Bell S, Maussion G, Jefri M, Peng H, Théroux J-F, Silveira H, Soubannier V, Wu H, Hu P, Galat E et al..  2018.  Disruption of GRIN2B Impairs Differentiation in Human Neurons.. Stem Cell Reports. 11(1):183-196.
Vaillancourt K, Yang J, Chen GG, Yerko V, Théroux J-F, Aouabed Z, Lopez A, Thibeault KC, Calipari ES, Labonte B et al..  2020.  Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster.. Mol Psychiatry.
Lutz P-E, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D et al..  2017.  Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence.. Am J Psychiatry. :appiajp201716111286.