Publications
Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells.. Stem Cell Reports. 16(7):1749-1762.
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2021. Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster.. Mol Psychiatry.
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2020. A roadmap for neurodevelopmental disease modeling for non-stem cell biologists.. Stem Cells Transl Med. 9(5):567-574.
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2020. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.. Stem Cells Transl Med. 9(6):697-712.
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2020. Dose in Brain Development.. Front Pediatr. 7:482.
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2019. Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons. The American Journal of Human Genetics.
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2019. Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.. Am J Hum Genet. 104(5):815-834.
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2019. Disruption of GRIN2B Impairs Differentiation in Human Neurons.. Stem Cell Reports. 11(1):183-196.
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2018. Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence.. Am J Psychiatry. :appiajp201716111286.
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2017. Cover Image, Volume 173A, Number 2, February 2017.. Am J Med Genet A. 173(2):i.
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2017. DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects.. Genes (Basel). 8(5)
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2017. Implication of LRRC4C and DPP6 in neurodevelopmental disorders.. Am J Med Genet A. 173(2):395-406.
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2017. Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine.. BMC Genomics. 18(1):96.
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2017. Potential molecular consequences of transgene integration: The R6/2 mouse example.. Sci Rep. 7:41120.
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2017. A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing.. Stem Cells Transl Med. 6(3):886-896.
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2017. Strategies to advance drug discovery in rare monogenic intellectual disability syndromes.. Int J Neuropsychopharmacol.
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2017. A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review.. Am J Med Genet A. 170A(5):1225-35.
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2016. Lesch-Nyhan Syndrome: Models, Theories, and Therapies.. Mol Syndromol. 7(6):302-311.
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2016. Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling.. Science. 351(6275):849-54.
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2016. Proliferation and Differentiation Deficits are a Major Convergence Point for Neurodevelopmental Disorders.. Trends Neurosci. 39(5):290-9.
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2016. Astrocytic abnormalities and global DNA methylation patterns in depression and suicide.. Mol Psychiatry. 20(3):320-8.
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2015. Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing.. BMC Med Genomics. 8:35.
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2015. Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution.. BMC Genomics. 16:672.
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