Publications

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2021
Gonneaud J, Baria AT, Binette APichet, Gordon BA, Chhatwal JP, Cruchaga C, Jucker M, Levin J, Salloway S, Farlow M et al..  2021.  Accelerated functional brain aging in pre-clinical familial Alzheimer's disease.. Nat Commun. 12(1):5346.
Picard C, Nilsson N, Labonte A, Auld D, Rosa-Neto P, Ashton NJ, Zetterberg H, Blennow K, Breitner JCS, Villeneuve S et al..  2021.  Apolipoprotein B is a novel marker for early tau pathology in Alzheimer's disease.. Alzheimers Dement.
Nilsson NIV, Picard C, Labonte A, Köbe T, Meyer P-F, Villeneuve S, Auld D, Poirier J.  2021.  Association of a Total Cholesterol Polygenic Score with Cholesterol Levels and Pathological Biomarkers across the Alzheimer's Disease Spectrum.. Genes (Basel). 12(11)
Binette APichet, Theaud G, Rheault F, Roy M, D Collins L, Levin J, Mori H, Lee JHong, Farlow MRhys, Schofield P et al..  2021.  Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease.. Elife. 10
Tremblay-Mercier J, Madjar C, Das S, Binette APichet, Dyke SOM, Etienne P, Lafaille-Magnan M-E, Remz J, Bellec P, D Collins L et al..  2021.  Open science datasets from PREVENT-AD, a longitudinal cohort of pre-symptomatic Alzheimer's disease.. Neuroimage Clin. 31:102733.
Köbe T, Binette APichet, Vogel JW, Meyer P-F, Breitner JCS, Poirier J, Villeneuve S.  2021.  Vascular risk factors are associated with a decline in resting-state functional connectivity in cognitively unimpaired individuals at risk for Alzheimer's disease: Vascular risk factors and functional connectivity changes.. Neuroimage. 231:117832.
2020
Binette APichet, Vachon-Presseau E, Morris J, Bateman R, Benzinger T, D Collins L, Poirier J, Breitner JCS, Villeneuve S.  2020.  Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease.. Biol Psychiatry.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Savard M, Chamoun M, Thomas É, Kang MSu, Lussier F, Tissot C et al..  2020.  APOEε4 potentiates the relationship between amyloid-β and tau pathologies.. Mol Psychiatry.
Gonneaud J, Bedetti C, Binette APichet, Benzinger TLS, Morris JC, Bateman RJ, Poirier J, Breitner JCS, Villeneuve S.  2020.  Association of education with Aβ burden in preclinical familial and sporadic Alzheimer disease.. Neurology. 95(11):e1554-e1564.
Baril A-A, Gagnon K, Descoteaux M, Bedetti C, Chami S, Sanchez E, Montplaisir J, De Beaumont L, Gilbert D, Poirier J et al..  2020.  Cerebral white matter diffusion properties and free-water with obstructive sleep apnea severity in older adults. Human brain mapping. 41(10):2686-2701.
Binette APichet, Gonneaud J, Vogel JW, La Joie R, Rosa-Neto P, D Collins L, Poirier J, Breitner JCS, Villeneuve S, Vachon-Presseau E.  2020.  Morphometric network differences in ageing versus Alzheimer's disease dementia.. Brain. 143(2):635-649.
2019
Fiocco AJ, D'Amico D, De Beaumont L, Poirier J, Lupien S.  2019.  Association between BDNF Polymorphism and Hypothalamic-Pituitary-Adrenal Activity in Later Adulthood.. Gerontology. :1-7.
Miron J, Picard C, Labonte A, Auld D, Breitner JCS, Poirier J.  2019.  Association of PPP2R1A with Alzheimer's disease and specific cognitive domains.. Neurobiol Aging. 81:234-243.
Miron J, Picard C, Lafaille-Magnan M-E, Savard M, Labonte A, Breitner JCS, Rosa-Neto P, Auld D, Poirier J.  2019.  Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation.. Alzheimers Dement. 15(7):951-960.
Liebsch F, Kulic L, Teunissen C, Shobo A, Ulku I, Engelschalt V, Hancock MA, van der Flier WM, Kunach P, Rosa-Neto P et al..  2019.  Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.. Nat Commun. 10(1):2240.
Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K et al..  2019.  The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study.. Can J Neurol Sci. 46(5):499-511.
Meyer P-F, Savard M, Poirier J, Morgan D, Breitner JCS.  2019.  Hypothesis: cerebrospinal fluid protein markers suggest a pathway toward symptomatic resilience to AD pathology.. Alzheimers Dement. 15(9):1160-1171.
Meyer P-F, Tremblay-Mercier J, Leoutsakos J, Madjar C, Lafaille-Maignan M-É, Savard M, Rosa-Neto P, Poirier J, Etienne P, Breitner JCS.  2019.  INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease.. Neurology. 92(18):e2070-e2080.
Lleó A, Alcolea D, Martínez-Lage P, Scheltens P, Parnetti L, Poirier J, Simonsen AH, Verbeek MM, Rosa-Neto P, Slot RER et al..  2019.  Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study.. Alzheimers Dement. 15(6):742-753.
Meyer P-F, Labonte A, Rosa-Neto P, Poirier J, Breitner JCS.  2019.  No apparent effect of naproxen on CSF markers of innate immune activation.. Ann Clin Transl Neurol. 6(6):1127-1133.
Picard C, Poirier A, Bélanger S, Labonte A, Auld D, Poirier J.  2019.  Proprotein convertase subtilisin/kexin type 9 (PCSK9) in Alzheimer's disease: A genetic and proteomic multi-cohort study.. PLoS One. 14(8):e0220254.
2018
Picard C, Julien C, Frappier J, Miron J, Théroux L, Dea D, Breitner JCS, Poirier J.  2018.  Alterations in cholesterol metabolism-related genes in sporadic Alzheimer's disease.. Neurobiol Aging. 66:180.e1-180.e9.
Meyer P-F, Savard M, Poirier J, Labonte A, Rosa-Neto P, Weitz TM, Town T, Breitner JCS.  2018.  Bi-directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer's Disease Pathogenesis.. J Alzheimers Dis. 63(2):577-590.
Vogel JW, Vachon-Presseau E, Binette APichet, Tam A, Orban P, La Joie R, Savard M, Picard C, Poirier J, Bellec P et al..  2018.  Brain properties predict proximity to symptom onset in sporadic Alzheimer's disease.. Brain. 141(6):1871-1883.
Miron J, Picard C, Nilsson N, Frappier J, Dea D, Théroux L, Poirier J.  2018.  CDK5RAP2 gene and tau pathophysiology in late-onset sporadic Alzheimer's disease.. Alzheimers Dement.

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