Publications

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Journal Article
Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang M-S, Gauthier S, Rouleau GA, Poirier J et al..  2018.   variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.. Neurol Genet. 4(1):e216.
Cruceanu C, Tan PPatrick Ch, Rogic S, Lopez JPablo, Torres-Platas SGabriela, Gigek CO, Alda M, Rouleau GA, Pavlidis P, Turecki G.  2015.  Transcriptome sequencing of the anterior cingulate in bipolar disorder: dysregulation of G protein-coupled receptors.. Am J Psychiatry. 172(11):1131-40.
Cruceanu C, Alda M, Dion PA, Turecki G, Rouleau GA.  2015.  No evidence for GADL1 variation as a bipolar disorder susceptibility factor in a Caucasian lithium-responsive cohort.. Am J Psychiatry. 172(1):94-5.
Girard SL, Dion PA, Bourassa CV, Geoffroy S, Lachance-Touchette P, Barhdadi A, Langlois M, Joober R, Krebs M-O, Dubé M-P et al..  2015.  Mutation burden of rare variants in schizophrenia candidate genes.. PLoS One. 10(6):e0128988.
Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M et al..  2018.  Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.. Bipolar Disord.
Forstner AJ, Hecker J, Hofmann A, Maaser A, Reinbold CS, Mühleisen TW, Leber M, Strohmaier J, Degenhardt F, Treutlein J et al..  2017.  Identification of shared risk loci and pathways for bipolar disorder and schizophrenia.. PLoS One. 12(2):e0171595.
Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Forstner AJ, Schumacher J, Breuer R et al..  2014.  Genome-wide association study reveals two new risk loci for bipolar disorder.. Nat Commun. 5:3339.
Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landen M, Adli M, Alda M, Ardau R, Arias B et al..  2016.  Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.. Hum Mol Genet. 25(15):3383-3394.
Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CEM et al..  2016.  Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.. Lancet. 387(10023):1085-93.
Mühleisen TW, Reinbold CS, Forstner AJ, Abramova LI, Alda M, Babadjanova G, Bauer M, Brennan P, Chuchalin A, Cruceanu C et al..  2018.  Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder.. J Affect Disord. 228:20-25.
Ambalavanan A, Chaumette B, Zhou S, Xie P, He Q, Spiegelman D, Dionne-Laporte A, Bourassa CV, Therrien M, Rochefort D et al..  2018.  Exome sequencing of sporadic childhood-onset schizophrenia suggests the contribution of X-linked genes in males.. Am J Med Genet B Neuropsychiatr Genet.
Cruceanu C, Kutsarova E, Chen ES, Checknita DR, Nagy C, Lopez JPablo, Alda M, Rouleau GA, Turecki G.  2016.  DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression.. BMC Psychiatry. 16(1):286.
Catoire H, Sarayloo F, Amari KMourabit, Apuzzo S, Grant A, Rochefort D, Xiong L, Montplaisir J, Earley CJ, Turecki G et al..  2018.  A direct interaction between two Restless Legs Syndrome predisposing genes: MEIS1 and SKOR1.. Sci Rep. 8(1):12173.
Gan-Or, iv Z, Montplaisir JY, Ross JP, Poirier J, Warby SC, Arnulf I, Strong S, Dauvilliers Y, Leblond CS, Hu MTM et al..  2017.  The dementia-associated APOE ε4 allele is not associated with rapid eye movement sleep behavior disorder.. Neurobiol Aging. 49:218.e13-218.e15.
Huzayyin AA, Andreazza AC, Turecki G, Cruceanu C, Rouleau GA, Alda M, L Young T.  2014.  Decreased global methylation in patients with bipolar disorder who respond to lithium.. Int J Neuropsychopharmacol. 17(4):561-9.
Ambalavanan A, Girard SL, Ahn K, Zhou S, Dionne-Laporte A, Spiegelman D, Bourassa CV, Gauthier J, Hamdan FF, Xiong L et al..  2016.  De novo variants in sporadic cases of childhood onset schizophrenia.. Eur J Hum Genet. 24(6):944-8.
Merner N, d'Arc BForgeot, Bell SC, Maussion G, Peng H, Gauthier J, Crapper L, Hamdan FF, Michaud JL, Mottron L et al..  2016.  A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review.. Am J Med Genet A. 170A(5):1225-35.
Amare AT, Schubert KOliver, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu Y-H, Shekhtman T et al..  2018.  Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.. JAMA Psychiatry. 75(1):65-74.
Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K et al..  2018.  Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.. Front Psychiatry. 9:207.
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R et al..  2018.  Analysis of shared heritability in common disorders of the brain.. Science. 360(6395)