Publications

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Journal Article
Sharafi SMehran, Sylvestre J-P, Chevrefils C, Soucy J-P, Beaulieu S, Pascoal TA, Arbour JDaniel, Rhéaume M-A, Robillard A, Chayer C et al..  2019.  Vascular retinal biomarkers improves the detection of the likely cerebral amyloid status from hyperspectral retinal images.. Alzheimers Dement (N Y). 5:610-617.
Therriault J, Pascoal TA, Savard M, Benedet AL, Chamoun M, Tissot C, Lussier F, Kang MSu, Thomas É, Terada T et al..  2020.  Topographical distribution of amyloid-β, tau and atrophy in behavioral / dysexecutive AD patients.. Neurology.
Pascoal TA, Mathotaarachchi S, Shin M, Benedet AL, Mohades S, Wang S, Beaudry T, Kang MSu, Soucy J-P, Labbe A et al..  2017.  Synergistic interaction between amyloid and tau predicts the progression to dementia.. Alzheimers Dement. 13(6):644-653.
Ng KPin, Therriault J, Kang MSu, Struyfs H, Pascoal TA, Mathotaarachchi S, Shin M, Benedet AL, Massarweh G, Soucy J-P et al..  2019.  Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [F]THK5351 uptake in progressive supranuclear palsy.. Neuroimage Clin. 24:102091.
Schirrmacher R, Bailey JJ, Mossine AV, Scott PJH, Kaiser L, Bartenstein P, Lindner S, Kaplan DR, Kostikov A, Fricker G et al..  2019.  Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging.. Pharmaceuticals (Basel). 12(1)
Pascoal TA, Benedet AL, Ashton NJ, Kang MSu, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK et al..  2021.  Publisher Correction: Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(11):2048-2049.
Kang MSu, Shin M, Ottoy J, Aliaga AAliaga, Mathotaarachchi S, Quispialaya K, Pascoal TA, D Collins L, Chakravarty MM, Mathieu A et al..  2021.  Preclinical longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease therapeutic.. J Cereb Blood Flow Metab. :271678X211035625.
Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy J-P, Aliaga A, Kostikov A, Maclaren DAA, Clark SD, Bedard M-A.  2014.  PET imaging with [¹⁸F]fluoroethoxybenzovesamicol ([¹⁸F]FEOBV) following selective lesion of cholinergic pedunculopontine tegmental neurons in rat.. Nucl Med Biol. 41(1):96-101.
Legault-Denis C, Aghourian M, Soucy J-P, Rosa-Neto P, Dagher A, Aumont É, Wickens R, Bedard M-A.  2021.  Normal cognition in Parkinson's disease may involve hippocampal cholinergic compensation: An exploratory PET imaging study with [F]-FEOBV.. Parkinsonism Relat Disord. 91:162-166.
Hadoux X, Hui F, Lim JKH, Masters CL, Pébay A, Chevalier S, Ha J, Loi S, Fowler CJ, Rowe C et al..  2019.  Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease.. Nat Commun. 10(1):4227.
Parent MJ, Zimmer ER, Shin M, Kang MSu, Fonov VS, Mathieu A, Aliaga A, Kostikov A, Carmo SDo, Dea D et al..  2017.  Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities.. J Neurosci. 37(50):12263-12271.
Ng KPin, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MSu, Shin M, Guiot M-C, Guo Q, Harada R, Comley RA et al..  2017.  Monoamine oxidase B inhibitor, selegiline, reduces (18)F-THK5351 uptake in the human brain.. Alzheimers Res Ther. 9(1):25.
Kanel P, Bedard M-A, Aghourian M, Rosa-Neto P, Soucy J-P, Albin RL, Bohnen NI.  2021.  Molecular Imaging of the Cholinergic System in Alzheimer and Lewy Body Dementias: Expanding Views.. Curr Neurol Neurosci Rep. 21(10):52.
Pascoal TA, Benedet AL, Ashton NJ, Kang MSu, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK et al..  2021.  Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(9):1592-1599.
DuBois JM, Rousset OG, Guiot M-C, Hall JA, Reader AJ, Soucy J-P, Rosa-Neto P, Kobayashi E.  2016.  Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [11C]ABP688 Positron-Emission Tomography (PET) Imaging.. Cereb Cortex.
Pascoal TA, Benedet AL, Tudorascu DL, Therriault J, Mathotaarachchi S, Savard M, Lussier FZ, Tissot C, Chamoun M, Kang MSu et al..  2021.  Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.. Brain. 144(11):3517-3528.
DuBois JM, Mathotaarachchi S, Rousset OG, Sziklas V, Sepulcre J, Guiot M-C, Hall JA, Massarweh G, Soucy J-P, Rosa-Neto P et al..  2021.  Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia.. Neuroimage Clin. 29:102552.
Bernard-Gauthier V, Bailey JJ, Mossine AV, Lindner S, Vomacka L, Aliaga A, Shao X, Quesada CA, Sherman P, Mahringer A et al..  2017.  A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human.. J Med Chem. 60(16):6897-6910.
Pascoal TA, Shin M, Kang MSu, Chamoun M, Chartrand D, Mathotaarachchi S, Bennacef I, Therriault J, Ng KPin, Hopewell R et al..  2018.  In vivo quantification of neurofibrillary tangles with [F]MK-6240.. Alzheimers Res Ther. 10(1):74.
Leuzy A, Zimmer ERigon, Dubois J, Pruessner J, Cooperman C, Soucy J-P, Kostikov A, Schirmaccher E, Désautels R, Gauthier S et al..  2015.  In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD.. Brain Struct Funct.
Zimmer ER, Parent MJ, Leuzy A, Aliaga A, Aliaga A, Moquin L, Schirrmacher ES, Soucy J-P, Skelin I, Gratton A et al..  2015.  Imaging in vivo glutamate fluctuations with [(11)C]ABP688: a GLT-1 challenge with ceftriaxone.. J Cereb Blood Flow Metab. 35(7):1169-74.
Therriault J, Pascoal TA, Benedet AL, Tissot C, Savard M, Chamoun M, Lussier F, Kang MSu, Berzgin G, Wang T et al..  2021.  Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, ε4, and Cognitive Impairment.. Neurology. 96(7):e975-e985.
Bailey JJ, Kaiser L, Lindner S, Wüst M, Thiel A, Soucy J-P, Rosa-Neto P, Scott PJH, Unterrainer M, Kaplan DR et al..  2019.  First-in-Human Brain Imaging of [F]TRACK, a PET tracer for Tropomyosin Receptor Kinases.. ACS Chem Neurosci. 10(6):2697-2702.
Aghourian M, Aumont É, Grothe MJ, Soucy J-P, Rosa-Neto P, Bedard M-A.  2021.  FEOBV-PET to quantify cortical cholinergic denervation in AD: Relationship to basal forebrain volumetry.. J Neuroimaging. 31(6):1077-1081.
Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy J-P, Clark SD, Aghourian M, Bedard M-A.  2015.  Deficit in sustained attention following selective cholinergic lesion of the pedunculopontine tegmental nucleus in rat, as measured with both post-mortem immunocytochemistry and in vivo PET imaging with [¹⁸F]fluoroethoxybenzovesamicol.. Behav Brain Res. 278:107-14.

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