Publications

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Journal Article
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R et al..  2018.  Analysis of shared heritability in common disorders of the brain.. Science. 360(6395)
Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K et al..  2018.  Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.. Front Psychiatry. 9:207.
Amare AT, Schubert KOliver, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu Y-H et al..  2020.  Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.. Mol Psychiatry.
Amare AT, Schubert KOliver, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu Y-H, Shekhtman T et al..  2018.  Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.. JAMA Psychiatry. 75(1):65-74.
Lopez JPablo, Diallo A, Cruceanu C, Fiori LM, Laboissiere S, Guillet I, Fontaine J, Ragoussis J, Benes V, Turecki G et al..  2015.  Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing.. BMC Med Genomics. 8:35.
Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NMenjot et al..  2017.  Cover Image, Volume 173A, Number 2, February 2017.. Am J Med Genet A. 173(2):i.
Huzayyin AA, Andreazza AC, Turecki G, Cruceanu C, Rouleau GA, Alda M, L Young T.  2014.  Decreased global methylation in patients with bipolar disorder who respond to lithium.. Int J Neuropsychopharmacol. 17(4):561-9.
Cruceanu C, Kutsarova E, Chen ES, Checknita DR, Nagy C, Lopez JPablo, Alda M, Rouleau GA, Turecki G.  2016.  DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression.. BMC Psychiatry. 16(1):286.
Nagy C, Maheu M, Lopez JPablo, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G.  2015.  Effects of postmortem interval on biomolecule integrity in the brain.. J Neuropathol Exp Neurol. 74(5):459-69.
Torres-Platas SG, Cruceanu C, Chen GGang, Turecki G, Mechawar N.  2014.  Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides.. Brain Behav Immun. 42:50-9.
Papadima EMerkouri, Niola P, Melis C, Pisanu C, Congiu D, Cruceanu C, Lopez JPablo, Turecki G, Ardau R, Severino G et al..  2017.  Evidence towards RNA Binding Motif (RNP1, RRM) Protein 3 (RBM3) as a Potential Biomarker of Lithium Response in Bipolar Disorder Patients.. J Mol Neurosci. 62(3-4):304-308.
Mühleisen TW, Reinbold CS, Forstner AJ, Abramova LI, Alda M, Babadjanova G, Bauer M, Brennan P, Chuchalin A, Cruceanu C et al..  2018.  Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder.. J Affect Disord. 228:20-25.
Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CEM et al..  2016.  Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.. Lancet. 387(10023):1085-93.
Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landen M, Adli M, Alda M, Ardau R, Arias B et al..  2016.  Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.. Hum Mol Genet. 25(15):3383-3394.
Forstner AJ, Hecker J, Hofmann A, Maaser A, Reinbold CS, Mühleisen TW, Leber M, Strohmaier J, Degenhardt F, Treutlein J et al..  2017.  Identification of shared risk loci and pathways for bipolar disorder and schizophrenia.. PLoS One. 12(2):e0171595.
Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NMenjot et al..  2017.  Implication of LRRC4C and DPP6 in neurodevelopmental disorders.. Am J Med Genet A. 173(2):395-406.
Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M et al..  2018.  Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.. Bipolar Disord.
Squassina A, Pisanu C, Congiu D, Caria P, Frau D, Niola P, Melis C, Baggiani G, Lopez JPablo, Cruceanu C et al..  2016.  Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients.. Eur Neuropsychopharmacol. 26(7):1241-7.
Squassina A, Niola P, Lopez JPablo, Cruceanu C, Pisanu C, Congiu D, Severino G, Ardau R, Chillotti C, Alda M et al..  2020.  MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings.. Eur Neuropsychopharmacol. 34:39-49.
Lopez JPablo, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C et al..  2017.  MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.. Nat Commun. 8:15497.
Lopez JPablo, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, Maussion G, Yang JP, Yerko V, Vigneault E et al..  2014.  miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment.. Nat Med. 20(7):764-8.
Torres-Platas SG, Comeau S, Rachalski A, Dal Bo G, Cruceanu C, Turecki G, Giros B, Mechawar N.  2014.  Morphometric characterization of microglial phenotypes in human cerebral cortex.. J Neuroinflammation. 11:12.
Cruceanu C, Alda M, Dion PA, Turecki G, Rouleau GA.  2015.  No evidence for GADL1 variation as a bipolar disorder susceptibility factor in a Caucasian lithium-responsive cohort.. Am J Psychiatry. 172(1):94-5.
Cruceanu C, Tan PPatrick Ch, Rogic S, Lopez JPablo, Torres-Platas SGabriela, Gigek CO, Alda M, Rouleau GA, Pavlidis P, Turecki G.  2015.  Transcriptome sequencing of the anterior cingulate in bipolar disorder: dysregulation of G protein-coupled receptors.. Am J Psychiatry. 172(11):1131-40.