Publications
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18F-MK-6240 PET for early and late detection of neurofibrillary tangles.. Brain. 143(9):2818-2830.
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2020. Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease.. Eur J Nucl Med Mol Imaging. 45(6):1021-1030.
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2018. Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer's disease.. Mol Psychiatry.
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2020. Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia.. Ann Clin Transl Neurol. 8(10):2083-2092.
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2021. Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.. Neurology. 90(11):e932-e939.
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2020. Author response: Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.. Neurology. 89(18):1931.
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2017. Characterizing biomarker features of cognitively normal individuals with ventriculomegaly.. Alzheimers Dement (Amst). 10:12-21.
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2019. Epistasis analysis links immune cascades and cerebral amyloidosis.. J Neuroinflammation. 12:227.
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2015. Identifying incipient dementia individuals using machine learning and amyloid imaging.. Neurobiol Aging. 59:80-90.
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2017. In vivo quantification of neurofibrillary tangles with [F]MK-6240.. Alzheimers Res Ther. 10(1):74.
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2018. Interactive rather than independent effect of and sex potentiates tau deposition in women.. Brain Commun. 3(2):fcab126.
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2021. Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia.. Neuroimage Clin. 29:102552.
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2021. Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.. Brain. 144(11):3517-3528.
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2021. Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(9):1592-1599.
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2021. Monoamine oxidase B inhibitor, selegiline, reduces (18)F-THK5351 uptake in the human brain.. Alzheimers Res Ther. 9(1):25.
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2017. Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.. Neurology. 88(19):1814-1821.
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2019. Preclinical longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease therapeutic.. J Cereb Blood Flow Metab. :271678X211035625.
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2021. The prevalence and biomarkers' characteristic of rapidly progressive Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database.. Alzheimers Dement (N Y). 3(1):107-113.
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2017. Publisher Correction: Microglial activation and tau propagate jointly across Braak stages.. Nat Med. 27(11):2048-2049.
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2021. Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [F]THK5351 uptake in progressive supranuclear palsy.. Neuroimage Clin. 24:102091.
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2018. Suicidal ideation is common in autosomal dominant Alzheimer's disease at-risk persons.. Int J Geriatr Psychiatry. 35(1):60-68.
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