Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm.

TitlePregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm.
Publication TypeJournal Article
Year of Publication2016
AuthorsCao-Lei L, Dancause KN, Elgbeili G, Laplante DP, Szyf M, King S
JournalEarly Hum Dev
Volume103
Pagination189-192
Date Published2016 Dec
ISSN1872-6232
Abstract

We determined the extent to which DNA methylation mediates the effects of maternal cognitive appraisal of a natural disaster during pregnancy on offspring growth at age 13. Negative maternal cognitive appraisal predicted both lower BMI and central adiposity via DNA methylation of diabetes-related genes, suggesting a protective role of epigenetics.

DOI10.1016/j.earlhumdev.2016.09.013
Alternate JournalEarly Hum. Dev.
PubMed ID27718477

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