PET/CT of Dementia.
| Title | PET/CT of Dementia. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Zukotynski K, Kuo PH, Mikulis D, Rosa-Neto P, Strafella AP, Subramaniam RM, Black SE |
| Journal | AJR Am J Roentgenol |
| Volume | 211 |
| Issue | 2 |
| Pagination | 246-259 |
| Date Published | 2018 Aug |
| ISSN | 1546-3141 |
| Abstract | OBJECTIVE: In this article, we review the literature on PET/CT in the management of dementia, present evidence for best clinical practices, and discuss recent advances in the field.CONCLUSION: Standard-of-care imaging for dementia includes CT and MRI, primarily for excluding vascular lesions or masses, detecting atrophy, and monitoring disease severity. PET/CT is a powerful functional modality that can differentiate dementia types and influence management. Fluorine-18-FDG PET/CT reveals the spatial pattern of glucose metabolism in the brain. More recently, radiotracers for PET have been developed that bind to amyloid protein, tau protein, and neuroinflammatory markers. |
| DOI | 10.2214/AJR.18.19822 |
| Alternate Journal | AJR Am J Roentgenol |
| PubMed ID | 29949415 |