PET/CT of Dementia.
Title | PET/CT of Dementia. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Zukotynski K, Kuo PH, Mikulis D, Rosa-Neto P, Strafella AP, Subramaniam RM, Black SE |
Journal | AJR Am J Roentgenol |
Volume | 211 |
Issue | 2 |
Pagination | 246-259 |
Date Published | 2018 Aug |
ISSN | 1546-3141 |
Abstract | OBJECTIVE: In this article, we review the literature on PET/CT in the management of dementia, present evidence for best clinical practices, and discuss recent advances in the field.CONCLUSION: Standard-of-care imaging for dementia includes CT and MRI, primarily for excluding vascular lesions or masses, detecting atrophy, and monitoring disease severity. PET/CT is a powerful functional modality that can differentiate dementia types and influence management. Fluorine-18-FDG PET/CT reveals the spatial pattern of glucose metabolism in the brain. More recently, radiotracers for PET have been developed that bind to amyloid protein, tau protein, and neuroinflammatory markers. |
DOI | 10.2214/AJR.18.19822 |
Alternate Journal | AJR Am J Roentgenol |
PubMed ID | 29949415 |