PET/CT of Dementia.

TitlePET/CT of Dementia.
Publication TypeJournal Article
Year of Publication2018
AuthorsZukotynski K, Kuo PH, Mikulis D, Rosa-Neto P, Strafella AP, Subramaniam RM, Black SE
JournalAJR Am J Roentgenol
Volume211
Issue2
Pagination246-259
Date Published2018 Aug
ISSN1546-3141
Abstract

OBJECTIVE: In this article, we review the literature on PET/CT in the management of dementia, present evidence for best clinical practices, and discuss recent advances in the field.CONCLUSION: Standard-of-care imaging for dementia includes CT and MRI, primarily for excluding vascular lesions or masses, detecting atrophy, and monitoring disease severity. PET/CT is a powerful functional modality that can differentiate dementia types and influence management. Fluorine-18-FDG PET/CT reveals the spatial pattern of glucose metabolism in the brain. More recently, radiotracers for PET have been developed that bind to amyloid protein, tau protein, and neuroinflammatory markers.

DOI10.2214/AJR.18.19822
Alternate JournalAJR Am J Roentgenol
PubMed ID29949415