Licit and illicit substance use among people who inject drugs and the association with subsequent suicidal attempt.

TitleLicit and illicit substance use among people who inject drugs and the association with subsequent suicidal attempt.
Publication TypeJournal Article
Year of Publication2015
AuthorsArtenie AAdelina, Bruneau J, Roy É, Zang G, Lespérance F, Renaud J, Tremblay J, Jutras-Aswad D
Date Published2015 Oct
KeywordsAdult, Alcohol Drinking, Alcoholism, Amphetamine-Related Disorders, Cocaine-Related Disorders, Female, Humans, Hypnotics and Sedatives, Male, Marijuana Smoking, Mental Disorders, Middle Aged, Multivariate Analysis, Opioid-Related Disorders, Quebec, Risk Factors, Street Drugs, Substance Abuse, Intravenous, Suicide, Attempted

AIM: To estimate associations between recent licit and illicit substance use and subsequent suicide attempt among people who inject drugs (PWID).DESIGN: Secondary analysis of longitudinal data from a prospective cohort study of PWID followed bi-annually between 2004 and 2011.SETTING: Montréal, Canada.PARTICIPANTS: Seven hundred and ninety-seven PWID who reported injection drug use in the previous 6 months, contributing to a total of 4460 study visits. The median number of visits per participant was five (interquartile range: 3-8).MEASUREMENTS: An interviewer-administered questionnaire eliciting information on socio-demographic factors, detailed information on substance use patterns and related behaviours, mental health markers and suicide attempt. The primary exposure variables examined were past-month use of alcohol [heavy (≥ 60 drinks); moderate (one to 59 drinks); none], sedative-hypnotics, cannabis, cocaine, amphetamine and opioids [regular (≥ 4 days); occasional (1-3 days); none]. The outcome was a binary measure of suicide attempt assessed in reference to the previous 6 months.FINDINGS: In multivariate analyses, a positive association was found among licit substances between heavy alcohol consumption [adjusted odds ratio (AOR) = 2.05; 95% confidence interval (CI) = 1.12-3.75], regular use of sedative-hypnotics (AOR = 1.89; 95% CI = 1.21-2.95) and subsequent attempted suicide. Among illicit substances, occasional use of cannabis (AOR = 1.84; 95% CI = 1.09-3.13) had a positive association with subsequent suicide attempt. No statistically significant association was found for the remaining substances.CONCLUSION: Among people who inject drugs, use of alcohol, sedative-hypnotics and cannabis, but not cocaine, amphetamine or opioids, appears to be associated with an increased likelihood of later attempted suicide.

Alternate JournalAddiction
PubMed ID26119212
Grant ListMOP135260 / / Canadian Institutes of Health Research / Canada
MOP210232 / / Canadian Institutes of Health Research / Canada