6875 Boulevard Lasalle
Joseph Rochford, PhD
Director, Neurophenotyping Centre, Douglas Institute
Associate Professor, Department of Psychiatry, McGill University
Director, Integrated Program in Neuroscience, McGill University
Animal models, behavioral pharmacology, behavioural phenotyping
Advances in our understanding of environmental influences and molecular biology on neuronal and psychological development have allowed for the creation of more sophisticated and valid models of neurological and psychiatric disorders. Joseph Rochford, PhD and his team in the Neurophenotyping Centre provide consultation and phenotyping services to all members of the scientific community of Quebec and Canada interested in assessing the behavioural impact of genes, the environment, and their interaction.
Joseph Rochford is also actively involved in educational and training initiatives.
Rousse, I; Beaulieu, S; Rowe, W; Meaney, M J; Barden, N; Rochford, J. Spatial memory in transgenic mice with impaired glucocorticoid receptor function. Neuroreport 8, 841-845, 1997.
Rochford, J; Beaulieu, S; Rousse, I; Glowa, J R; Barden, N. Behavioral reactivity to aversive stimuli in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: effects of diazepam and FG-7142.et al. Psychopharmacology 132, 145-152, 1997.
Rowe, W B; Spreekmeester, E; Meaney, M J; Quirion, R; Rochford, J; et al. Reactivity to novelty in cognitively-impaired and cognitively-unimpaired aged rats and young rats. Neuroscience 83, 669-680, 1998.
Spreekmeester, E; Rochford, J. Selective mu and delta, but not kappa, opiate receptor antagonists inhibit the habituation of novelty-induced hypoalgesia in the rat. Psychopharmacology 148, 99-105, 2000.
Mar, A; Spreekmeester, E; Rochford, J, Antidepressants preferentially enhance habituation to novelty in the olfactory bulbectomized rat.National Library of Medicine. Psychopharmacology 150, 52-60, 2000.
Cook D; Nuro E; Jones EV; Altimimi HF; Farmer WT; Gandin V; Hanna E; Zong R; Barbon A; Nelson DL; Topisirovic I; Rochford J; Stellwagen D; Beique JC; Murai KK. FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation
Cell Reports. 9(4):1402-16, 2014.
FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation. Cell Rep. 2014;9(4):1402-16.
A controlled evaluation of a targeted early case detection intervention for reducing delay in treatment of first episode psychosis. Soc Psychiatry Psychiatr Epidemiol. 2014;49(11):1711-8.