Jacques Tremblay MD, MSc, BA
6875 Boulevard LaSalle
Researcher, Douglas Research Centre
General Practitioner, Department of Psychiatry, Douglas Mental Health University Institute
Councilior, Council of physicians, dentists, and pharmacists, CIUSSS ODIM
Assistant Professor, Department of Psychiatry, McGill University
General Practitioner, Departments of Psychiatry and General Medicine, CIUSSS de l'Outaouais
Clinical epidemiology in mental health
-Introduction of the concept of quality of medical care assessment using explicit and implicit criteria in Canada, following the world first clinical trial of Drug Use Review (DUR), conducted under US funding (Grant HS-03971), in the eighties. This concept is now used widely in North America, for purposes of institutional certification, and is the main quality of care assessment method used, and recommended by the Quebec College of Physicians.
-Participation in several clinical studies on substance abusers and their treatment, with a randomized clinical trial (RCT) of aftercare treatment for the multiple substances abuser. This contributed to externally validate evidence for the effectiveness of behavioural cognitive and AA-oriented group therapy. This researcher was responsible for original trial design. These studies have succeeded to lay a foundation for evidence-based practice in this area of the addictions. (1992 - 2003).
-Analysis of population survey data from Quechua Indians in Peru, measuring the long-term effects of protracted political violence on mental health. This research documented local idioms of distress using an ethnographic approach, and integrated a trauma questionnaire to measures of anxiety and depression, this researcher modeling the relationship between the degree of exposure to protracted violence, migratory status, and mental health variables (2001-2009).
-Participation in the development of indicators, from psychosocial, biological, and demographic dimensions, to predict recidivism of Driving under the Influence of Alcohol (DUI). This researcher was responsible for the biological dimension of this indicator development. Identification of cortisol reactivity as best predictor of DUI recidivism, in collaboration. Participation in the development and conduct of a RCT to test the effectiveness of Brief Motivational Interviewing among DUI recidivists, and impact of sleep deprivation and alcohol on young driver performance (2002+).
-Participation in a number of studies on the role of psychiatrists and general practitioners in mental health practice, and in the assessment of patient need severity following the implementation of the Quebec Mental Health Action Plan, from the patient perspective. This researcher is co-directed the later, under CIHR funding (2003+).
-Participation in a research team dedicated to the development of an epidemiological catchment area in the South-West of Montreal, in the area of mental health. This researcher contributed in the area of substance abuse and clinical medicine, and acted as medical officer for diagnostic divulgation, and for referral to appropriate services (2006+).
-Participation in the design and conduct of several RCT to assess the effectiveness of reconsolidation blockade (RB) for the emotional component of traumatic memories under medication in Post-Traumatic Stress Disorder (PTSD). Participation in an international research group including the American VA, Toulouse and Harvard Universities, to test the effectiveness of various medications in RB for PTSD patients, and in animal models using behavioural and neuro-chemical models. This researcher acted as medical officer for the conduct of Canadian trials of propranolol, to test RB effectiveness in PTSD, and drug craving (2007+).
Brown, T.G., Seraganian, P., Tremblay, J. & Annis, H. (2002). Process and outcome changes with relapse prevention versus 12-Step aftercare programs for substance abusers. Addiction, 97, 677-689.
Brunet, J., Orr, S., Tremblay, J., Robertson, K., Nader, K. & Pitman, R.K. (2008). Effect of post-retrieval propranolol on psychophysiologic responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder. Journal of Psychiatric Research, 42(6), 503-506.
Lasry, N., Levy, E. & Tremblay, J. (2008). Making Memories, Again. A Comment on: J.D. Karpicke & H.L. Roediger III. The Critical Importance of Retrieval for Learning. Science 2008; 319: 966-968. Science, 320(5884), 1720.
Tremblay, J., Pedersen, D. & Errazuriz, C. (2009). Assessing mental health outcomes of political violence and civil unrest in Peru. International Journal of Social Psychiatry, 55(5), 449-63.
Brown, T.G., Dongier, M., Ouimet, M.C., Tremblay, J., Chanut, F., Legault, L. & Ng Ying Kin, N.M.K. (2010). Brief Motivational Interviewing for DWI recidivists who abuse alcohol and are not participating in DWI intervention: a randomized controlled trial. Alcoholism: Clinical and Experimental Research, 34(2), 1-10.
Brunet, A., Poundja, J., Tremblay, J., Bui, E., Thomas, E., Orr, S.P., Azzoug, A., Birmes, P. & Pitman, R.K. (2011). Trauma Reactivation under the Influence of Propranolol Decreases Posttraumatic Stress Symptoms and Disorder: 3 Open-Label Trials. Journal of Clinical Psychopharmacology, 31(4), 547-550.
Caron, J., Fleury, M.J., Perreault, M., Crocker, A., Tremblay, J., Tousignant, M., Kestens, Y., Cargo, M. & Daniel, M. (2012). Prevalence of psychological distress and mental disorders, and use of mental health services in the epidemiological catchment area of Montreal South-West. BMC Psychiatry, 12, 183 - DOI: 10.1186/1471-244X-12-183.
Ouimet, M.C., Dongier, M., Di Leo, I., Legault, L., Tremblay, J., Chanut, F. & Brown, T.G. (2013). A Randomized Controlled Trial of Brief Motivational Interviewing in Impaired Driving Recidivists: A 5-Year Follow-Up of Traffic Offenses and Crashes. Alcoholism Clinical & Experimental Research, 37(11), 1979-85 - DOI: 10.1111/acer.12180.
Tremblay, J, Bamvita, J.M., Grenier, G., Fleury, M.J. (2014). Utility of the Montreal Assessment of Need Questionnaire for Community Mental Health Planning. Journal of Nervous and Mental Disease, 202(9):677-687.
Couture, S., Ouimet, M.C., Gianoulakis, C., Tremblay, J., Ng, Ying Kin N., Brochu, S., Pruessner, J., Dedovic, K. & Brown, T.G. (2015). Lower Cortisol Activity is Associated with First-Time Driving while Impaired. Substance Abuse : Research and Treatment, 9:25-32. doi: 10.4137/SART.S21353.
Typologies of Individuals Attending an Addiction Rehabilitation Center Based on Diagnosis of Mental Disorders. J Subst Abuse Treat. 2016;71:68-78.
Remission from substance use disorders: A systematic review and meta-analysis. Drug Alcohol Depend. 2016;168:293-306.
Examining cortical thickness in male and female DWI offenders. Neurosci Lett. 2016;619:189-95.
Personality, Executive Control, and Neurobiological Characteristics Associated with Different Forms of Risky Driving. PLoS ONE. 2016;11(2):e0150227.
Propranolol's impact on cognitive performance in post-traumatic stress disorder. J Affect Disord. 2016;192:98-103.
Adequacy of Help Received by Individuals with Severe Mental Disorders After a Major Healthcare Reform in Quebec: Predictors and Changes at 5-Year Follow-Up. Adm Policy Ment Health. 2016;43(5):799-812.
Reactivating addiction-related memories under propranolol to reduce craving: A pilot randomized controlled trial. J Behav Ther Exp Psychiatry. 2016;50:245-9.
Sex Differences in the Personality and Cognitive Characteristics of First-Time DWI Offenders. J Stud Alcohol Drugs. 2015;76(6):928-34.
Licit and illicit substance use among people who inject drugs and the association with subsequent suicidal attempt. Addiction. 2015;110(10):1636-43.
Lower Cortisol Activity is Associated with First-Time Driving while Impaired. Subst Abuse. 2015;9:25-32.
Associations of substance use patterns with attempted suicide among persons who inject drugs: can distinct use patterns play a role? Drug Alcohol Depend. 2015;147:208-14.
Utility of the Montreal assessment of need questionnaire for community mental health planning. J Nerv Ment Dis. 2014;202(9):677-87.
Trauma reactivation plus propranolol is associated with durably low physiological responding during subsequent script-driven traumatic imagery. Can J Psychiatry. 2014;59(4):228-32.
Adequacy of help received among individuals with severe mental disorders. Adm Policy Ment Health. 2014;41(3):302-16.
Predictors of quality of life in a longitudinal study of users with severe mental disorders. Health Qual Life Outcomes. 2013;11:92.
Typology of persons with severe mental disorders. BMC Psychiatry. 2013;13:137.
Factors associated with needs of users with severe mental disorders. Psychiatr Q. 2013;84(3):363-79.
Clinical Practice Settings Associated with GPs Who Take on Patients with Mental Disorders. Healthc Policy. 2010;5(4):90-104.
Components associated with adequacy of help for consumers with severe mental disorders. Adm Policy Ment Health. 2010;37(6):497-508.
Variables associated with general practitioners taking on serious mental disorder patients. BMC Fam Pract. 2009;10:41.
Variables associated with general practitioners taking on patients with common mental disorders. Ment Health Fam Med. 2008;5(3):149-60.