Frontotemporal dementia and COVID-19: Hypothesis generation and roadmap for future research.

TitleFrontotemporal dementia and COVID-19: Hypothesis generation and roadmap for future research.
Publication TypeJournal Article
Year of Publication2020
AuthorsNg KPin, Chiew HJin, Hameed S, Ting SKang Seng, Ng A, Soo SAnn, Wong BYX, Lim L, Yong ACW, Mok VCT, Rosa-Neto P, Dominguez J, Kim SY, Hsiung GYRobin, Ikeda M, Miller BL, Gauthier S, Kandiah N
JournalAlzheimers Dement (N Y)
Volume6
Issue1
Paginatione12085
Date Published2020
ISSN2352-8737
Abstract

The COVID-19 pandemic has caused tremendous suffering for patients with dementia and their caregivers. We conducted a survey to study the impact of the pandemic on patients with mild frontotemporal dementia (FTD). Our preliminary findings demonstrate that patients with FTD have significant worsening in behavior and social cognition, as well as suffer greater negative consequences from disruption to health-care services compared to patients with AD. The reduced ability to cope with sudden changes to social environments places patients with FTD at increased vulnerability to COVID-19 infection as well as to poorer clinical and social outcomes. Caregivers of FTD patients also demonstrate high burden during crisis situations. A proportion of patients with FTD benefitted from use of web-based interactive platforms. In this article, we outline the priority areas for research as well as a roadmap for future collaborative research to ensure greatest benefit for patients with FTD and their caregivers.

DOI10.1002/trc2.12085
Alternate JournalAlzheimers Dement (N Y)
PubMed ID33490361
PubMed Central IDPMC7810128