Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm.
Title | Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Cao-Lei L, Dancause KN, Elgbeili G, Laplante DP, Szyf M, King S |
Journal | Early Hum Dev |
Volume | 103 |
Pagination | 189-192 |
Date Published | 2016 Dec |
ISSN | 1872-6232 |
Abstract | We determined the extent to which DNA methylation mediates the effects of maternal cognitive appraisal of a natural disaster during pregnancy on offspring growth at age 13. Negative maternal cognitive appraisal predicted both lower BMI and central adiposity via DNA methylation of diabetes-related genes, suggesting a protective role of epigenetics. |
DOI | 10.1016/j.earlhumdev.2016.09.013 |
Alternate Journal | Early Hum. Dev. |
PubMed ID | 27718477 |