Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm.
| Title | Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Cao-Lei L, Dancause KN, Elgbeili G, Laplante DP, Szyf M, King S |
| Journal | Early Hum Dev |
| Volume | 103 |
| Pagination | 189-192 |
| Date Published | 2016 Dec |
| ISSN | 1872-6232 |
| Abstract | We determined the extent to which DNA methylation mediates the effects of maternal cognitive appraisal of a natural disaster during pregnancy on offspring growth at age 13. Negative maternal cognitive appraisal predicted both lower BMI and central adiposity via DNA methylation of diabetes-related genes, suggesting a protective role of epigenetics. |
| DOI | 10.1016/j.earlhumdev.2016.09.013 |
| Alternate Journal | Early Hum. Dev. |
| PubMed ID | 27718477 |