@article{pmid32896602,

title = {Adolescents with borderline personality disorder show a higher response to stress but a lack of self-perception: Evidence through affective computing},

author = {Nadège Bourvis and Aveline Aouidad and Michel Spodenkiewicz and Giuseppe Palestra and Jonathan Aigrain and Axel Baptista and Jean-Jacques Benoliel and Mohamed Chetouani and David Cohen},

doi = {10.1016/j.pnpbp.2020.110095},

issn = {1878-4216},

year  = {2021},

date = {2021-12-01},

journal = {Prog Neuropsychopharmacol Biol Psychiatry},

volume = {111},

pages = {110095},

abstract = {Stress reactivity is a complex phenomenon associated with multiple and multimodal expressions and functions. Herein, we hypothesized that compared with healthy controls (HCs), adolescents with borderline personality disorder (BPD) would exhibit a stronger response to stressors and a deficit in self-perception of stress due to their lack of insight. Twenty adolescents with BPD and 20 matched HCs performed a socially evaluated mental arithmetic test to induce stress. We assessed self- and heteroperception using both human ratings and affective computing-based methods for the automatic extraction of 39 behavioral features (2D + 3D video recording) and 62 physiological features (Nexus-10 recording). Predictions were made using machine learning. In addition, salivary cortisol was measured. Human ratings showed that adolescents with BPD experienced more stress than HCs. Human ratings and automated machine learning indicated opposite results regarding self- and heteroperceived stress in adolescents with BPD compared to HCs. Adolescents with BPD had higher levels of heteroperceived stress than self-perceived stress. Similarly, affective computing achieved better classification for heteroperceived stress. HCs had an opposite profile; they had higher levels of self-perceived stress, and affective computing reached a better classification for self-perceived stress. We conclude that adolescents with BPD are more sensitive to stress and show a lack of self-perception (or insight). In terms of clinical implications, our affective computing measures may help distinguish hetero- vs. self-perceptions of stress in natural settings and may offer external feedback during therapeutic interaction.},

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pubstate = {published},

tppubtype = {article}

}

@article{pmid34521240,

title = {Suicide in French Polynesia: a retrospective analysis based on medicolegal documents and interview with family},

author = {Stephane Amadéo and Moerani Rereao and Germaine Vanquin David and NgocLam Nguyen and Monique Séguin and Guy Beauchamp and Patrick Favro and Heimana Trouche and Aurélia Malogne and Benjamin Goodfellow and Erick Gokalsing and Michel Spodenkiewicz and Aminata Sy and Yvana Bocage-Barthélémy and Johan Sebti and Annie Tuheiava and Louis Jehel and Diego De Leo},

doi = {10.1177/03000605211003452},

issn = {1473-2300},

year  = {2021},

date = {2021-09-01},

journal = {J Int Med Res},

volume = {49},

number = {9},

pages = {3000605211003452},

abstract = {OBJECTIVE: To analyse the epidemiological data on suicide in French Polynesia (FP).nnMETHODS: Data on suicides were collected from the Public Health Direction, Judicial Police Investigations Court of Justice records, the Centre d'Opérations et de Renseignements de la Gendarmerie, patient records for those hospitalized in psychiatry and from psychological autopsies.nnRESULTS: The dataset consisted of 316 suicide cases in FP over 25 years (1992-2016). In FP, suicide was more frequent in men (sex ratio 3.2:1), young people (mean age, 34.4 years) and individuals with previously diagnosed psychiatric disorders (100 of 316; 31.6%) The most common method of suicide was hanging (276 of 316; 87.3%). A history of previous suicide attempts was found in 25 of 56 (44.6%) of suicide cases, when documented. The most common potential triggering factors for suicide were emotional problems. The suicide rates have remained stable during 1992-2016 (mean 10.6/100 000 inhabitants per year), with periods of economic crises increasing suicide rates.nnCONCLUSIONS: These results provide valuable information to enable the effective targeting of suicide prevention strategies toward those at high risk. Economic crises had larger impacts in the French overseas territories than mainland France. Given the unprecedented economic impact of the Covid-19 pandemic in FP, there is an urgent need to implement suicide epidemiological surveillance and prevention programmes.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid32883150,

title = {Supportive effect of body contact care with ylang ylang aromatherapy and mobile intervention team for suicide prevention: A pilot study},

author = {Stéphane Amadéo and Ngoc Lam Nguyen and Taivini Teai and Patrick Favro and Aurélia Mulet and Nathalie Colin-Fagotin and Moerani Rereao and Aurélia Malogne and Michel De Simone and Géraldine Rioche and Virginie Gassion and Paul Pere and Alban Prokop and Fabienne Bernis and Pierre Dufour and Annie Tuheiava and Germaine Vanquin and Steve Vilhem and Erick Gokalsing and Michel Spodenkiewicz and Marianne Pradem and Monique Seguin and Guy Beauchamp and Pierre Thomas and Guillaume Vaiva and Louis Jehel},

doi = {10.1177/0300060520946237},

issn = {1473-2300},

year  = {2020},

date = {2020-09-01},

journal = {J Int Med Res},

volume = {48},

number = {9},

pages = {300060520946237},

abstract = {OBJECTIVES: To assess understudied, alternative suicide prevention modalities in a mental health care setting.nnMETHODS: This was a prospective study of patients (n = 140, 68 cases and 72 controls) who were admitted to hospital or who contacted an SOS suicide crisis line for suicidal ideation or attempts. Psychiatric diagnoses (Mini-International Neuropsychiatric Interview) and intensity of anxiety/depression/suicidality (Hamilton Anxiety Rating Scale, Montgomery-Åsberg Depression Rating Scale, and Beck Scale for Suicidal Ideation) were assessed. All intervention group subjects received a crisis card with a crisis line number, interviews with psychologists or volunteers and a telephone call on days 10 to 21, then 6 months later. These subjects also had a choice between two further 4-month interventions: body contact care or mobile intervention team visits.nnRESULTS: The interventions significantly reduced the number of suicide attempts and suicide (3%) at 6 months compared with the control condition (12%). There were fewer losses to follow-up in the intervention group (7.35%) than in the control group (9.72%).nnCONCLUSIONS: The results favour the implementation of integrated care and maintaining contact in suicide prevention.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid32455636,

title = {Clinical Genetics of Prolidase Deficiency: An Updated Review},

author = {Marta Spodenkiewicz and Michel Spodenkiewicz and Maureen Cleary and Marie Massier and Giorgos Fitsialos and Vincent Cottin and Guillaume Jouret and Céline Poirsier and Martine Doco-Fenzy and Anne-Sophie Lèbre},

doi = {10.3390/biology9050108},

issn = {2079-7737},

year  = {2020},

date = {2020-05-01},

journal = {Biology (Basel)},

volume = {9},

number = {5},

abstract = {Prolidase is a ubiquitous enzyme that plays a major role in the metabolism of proline-rich proteins. Prolidase deficiency is a rare autosomal recessive inborn metabolic and multisystemic disease, characterized by a protean association of symptoms, namely intellectual disability, recurrent infections, splenomegaly, skin lesions, auto-immune disorders and cytopenia. To our knowledge, no published review has assembled the different clinical data and research studies over prolidase deficiency. The aim of this study is to summarize the actual state of the art from the descriptions of all the patients with a molecular diagnosis of prolidase deficiency reported to date regarding the clinical, biological, histopathological features, therapeutic options and functional studies.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid31024356,

title = {The Quest for Meaning Around Self-Injurious and Suicidal Acts: A Qualitative Study Among Adolescent Girls},

author = {Salomé Grandclerc and Solene Spiers and Michel Spodenkiewicz and Marie Rose Moro and Jonathan Lachal},

doi = {10.3389/fpsyt.2019.00190},

issn = {1664-0640},

year  = {2019},

date = {2019-01-01},

journal = {Front Psychiatry},

volume = {10},

pages = {190},

abstract = { Suicide and non-suicidal self-injury (NSSI) are major problems in adolescent psychiatry and share numerous clinical characteristics. The principal objective of this study is to describe the subjective experience of adolescent girls and young women who present NSSI and/or suicidal behaviors and to determine the common aspects and the specificities of each experience.  This exploratory study is based on a procedure that is qualitative, phenomenological, and inductive. The data were collected from two semi-structured interviews each of 18 girls and young women aged 12-21 years, who were receiving care from a psychiatrist specializing in adolescents and who at least once had harmed themselves by NSSI or attempted suicide, or both. The thematic data analysis was performed by applying the methods of interpretative phenomenological analysis.  The results are described around four superordinate themes: relationships with the self, with others/otherness, with the body, and with death; they are then subdivided into 13 themes. Several themes appeared common to both types of behavior, especially the relational dimension of self-harming acts. The process of separation-individuation seems complex for these youth.  The results underline the relational aspects of the self-harming behavior (NSSI or suicidal) among adolescent girls. These aspects also appear to be expressed in the family sphere, the social sphere, in contact with peers, and also at a societal level when the community no longer addresses adolescents' difficulties. When the process of subjectification does not appear to reach completion, self-aggressive behavior is seen as an ultimate attempt to regain a feeling of autonomy.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid29191571,

title = {Distinguish self- and hetero-perceived stress through behavioral imaging and physiological features},

author = {Michel Spodenkiewicz and Jonathan Aigrain and Nadège Bourvis and Séverine Dubuisson and Mohamed Chetouani and David Cohen},

doi = {10.1016/j.pnpbp.2017.11.023},

issn = {1878-4216},

year  = {2018},

date = {2018-03-01},

journal = {Prog Neuropsychopharmacol Biol Psychiatry},

volume = {82},

pages = {107--114},

abstract = {Stress reactivity is a complex phenomenon associated to multiple and multimodal expressions. Response to stressors has an obvious survival function and may be seen as an internal regulation to adapt to threat or danger. The intensity of this internal response can be assessed as the self-perception of the stress response. In species with social organization, this response also serves a communicative function, so-called hetero-perception. Our study presents multimodal stress detection assessment - a new methodology combining behavioral imaging and physiological monitoring for analyzing stress from these two perspectives. The system is based on automatic extraction of 39 behavioral (2D+3D video recording) and 62 physiological (Nexus-10 recording) features during a socially evaluated mental arithmetic test. The analysis with machine learning techniques for automatic classification using Support Vector Machine (SVM) show that self-perception and hetero-perception of social stress are both close but different phenomena: self-perception was significantly correlated with hetero-perception but significantly differed from it. Also, assessing stress with SVM through multimodality gave excellent classification results (F1 score values: 0.9±0.012 for hetero-perception and 0.87±0.021 for self-perception). In the best selected feature subsets, we found some common behavioral and physiological features that allow classification of both self- and hetero-perceived stress. However, we also found the contributing features for automatic classifications had opposite distributions: self-perception classification was mainly based on physiological features and hetero-perception was mainly based on behavioral features.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid29753435,

title = {[Acceptability of the systematic screening of suicidal adolescents in emergency departments]},

author = {Gabrielle Stoven and Jonathan Lachal and Erick Gokalsing and Lucie Baux and Louis Jehel and Michel Spodenkiewicz},

doi = {10.1016/j.spsy.2018.03.006},

issn = {0241-6972},

year  = {2018},

date = {2018-01-01},

journal = {Soins Psychiatr},

volume = {39},

number = {316},

pages = {27--29},

abstract = {Studies of adolescent suicide screening tools have increased with the development of questionnaires that can be used in paediatric emergency departments. This article proposes a literature review of the acceptability of such interventions. Although these tools are well accepted when they are systematized, their usefulness is determined by the availability of child psychiatric care with the right balance between the adolescent's confidentiality and parental involvement.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid29753431,

title = {[An overview of suicide risk in adolescence]},

author = {Jonathan Lachal and Marie Rose Moro and Michel Spodenkiewicz},

doi = {10.1016/j.spsy.2018.03.002},

issn = {0241-6972},

year  = {2018},

date = {2018-01-01},

journal = {Soins Psychiatr},

volume = {39},

number = {316},

pages = {10--13},

abstract = {Suicidal behaviour in adolescence is a major public health issue. It is the consequence of a sum of individual, relational and environmental difficulties that weaken the subject in a period of great vulnerability. The main aspects of their care consist in developing a good therapeutic link and adapting the adolescent's environment. Prevention is the concern of everyone, especially healthcare professionals who are regularly consulted before suicidal acts.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid27093093,

title = {Catatonia and Autoimmune Conditions in Children and Adolescents: Should We Consider a Therapeutic Challenge?},

author = {Vladimir Ferrafiat and Marie Raffin and Kumaran Deiva and Xavier Salle-Collemiche and Anne Lepine and Michel Spodenkiewicz and Isabelle Michelet and Julien Haroche and Zahir Amoura and Priscille Gerardin and David Cohen and Angèle Consoli},

doi = {10.1089/cap.2015.0086},

issn = {1557-8992},

year  = {2017},

date = {2017-03-01},

journal = {J Child Adolesc Psychopharmacol},

volume = {27},

number = {2},

pages = {167--176},

abstract = {OBJECTIVE: Catatonia as a result of autoimmune conditions offers new therapeutic opportunities for patients that child and adolescent psychiatrists should consider. However, the diagnosis is sometimes challenging when an autoimmune signature is not identified.nnMETHODS: In this study, we aim to summarize seven cases from a 20-year series of 84 youths with catatonia, including three cases that represented a diagnostic challenge because of the absence of positive autoimmune testing.nnRESULTS: Immunosuppressive/modulatory treatment improved catatonic and psychotic features in all cases.nnCONCLUSION: To facilitate treatment decision-making, we propose a causality assessment score and a treatment algorithm, which may help clinicians consider whether an autoimmune condition is associated with catatonia.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid27089157,

title = {Relations between Nonsuicidal Self-Injury and Suicidal Behavior in Adolescence: A Systematic Review},

author = {Salome Grandclerc and Diane De Labrouhe and Michel Spodenkiewicz and Jonathan Lachal and Marie-Rose Moro},

doi = {10.1371/journal.pone.0153760},

issn = {1932-6203},

year  = {2016},

date = {2016-01-01},

journal = {PLoS One},

volume = {11},

number = {4},

pages = {e0153760},

abstract = {Nonsuicidal self-injury (NSSI) and suicidal behaviors, both important issues in adolescent health care, are frequently associated and possibly clinically related. Our objective was to explore the views of relations between nonsuicidal self-injury and suicidal behaviors during adolescence and young adulthood (11-25 years) expressed in the scientific (medical and psychological) literature. We adopted a textual approach to the process of synthesis to tell the story of the findings from the included studies. Our narrative systematic review of 64 articles found that they share the same risk factors. Integrated models envision nonsuicidal self-injury as a gateway enabling teens to acquire the capability for suicide. Because suicidal behavior short-circuits thought, it is difficult to conceive an intention to die during adolescents' acts of self-injury. Intention is constructed by the narrative of the act, influenced by numerous elements from the psychopathologic, cultural, religious, and philosophic context. Techniques of mentalizing-based treatments and work on the meaning that adolescents attribute to their behaviors might improve care.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid24223047,

title = {Living from day to day - qualitative study on borderline personality disorder in adolescence},

author = {Michel Spodenkiewicz and Mario Speranza and Olivier Taïeb and Alexandra Pham-Scottez and Maurice Corcos and Anne Révah-Levy},

issn = {1719-8429},

year  = {2013},

date = {2013-11-01},

journal = {J Can Acad Child Adolesc Psychiatry},

volume = {22},

number = {4},

pages = {282--289},

abstract = {OBJECTIVE: The purpose of this study was to assess how far identity and self-image disturbances are features of borderline personality disorder (BPD) in adolescence.nnMETHOD: Face-to-face interviews were carried out with a total of 50 adolescents with BPD and 50 controls, with a median age of 16 (SD 1.1; range 13 to 18) years. Data was analysed using a qualitative methodology, interpretative phenomenological analysis (IPA). Thematic statements representative of adolescents' lived experience were extracted from the interviews.nnRESULTS: Four main themes representing the day-to-day experiences of adolescents with BPD were identified: emotional experiences characterised by the feelings of fear, sadness and pessimism; interpersonal relationships characterised by the feelings of solitude and hostility from others; a conformist self-image characterised by a feeling of normality and difficulty in projecting into time; and, a structuring of discourse characterised by discontinuity in the perception of experiences.nnCONCLUSION: This qualitative study suggests that the day-to-day experiences of adolescents with borderline personality disorder is centred on the experience of the present. Discontinuity in self-image, alongside marked dysphoric manifestations, leads to distress and hinders compliance with care. These issues are highly relevant in psychotherapy and could lead to more effective treatment of the disorder in adolescents.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid22297097,

title = {Case report of Ganser syndrome in a 14-year-old girl: another face of depressive disorder?},

author = {Michel Spodenkiewicz and Olivier Taïeb and Mario Speranza and Marie-Rose Moro and Anne Révah-Levy},

doi = {10.1186/1753-2000-6-6},

issn = {1753-2000},

year  = {2012},

date = {2012-02-01},

journal = {Child Adolesc Psychiatry Ment Health},

volume = {6},

number = {1},

pages = {6},

abstract = {The Ganser syndrome is rare in children and in adolescents. A case of the Ganser syndrome in a 14-year-old girl, with three of the four essential features, is presented. After rapid resolution in two weeks, Ganser symptoms reappear seven months later accompanied, this second time, by previous depressive symptoms. This report raises the possibility of the Ganser syndrome as a manifestation of a depressive disorder in adolescence.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}