Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.

TitleInactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.
Publication TypeJournal Article
Year of Publication2020
AuthorsLavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch K-F, Linnaranta O
JournalBipolar Disord
Date Published2020 Mar 30
ISSN1399-5618
Abstract

BACKGROUND: Sleep problems are common in bipolar disorders (BDs). To objectively characterize these problems in BDs, further methodological development is needed to capture subjective insomnia.AIM: To test psychometric properties of the Athens Insomnia Scale (AIS), and associations with actigraphy-derived measures, applying modifications in actigraphy data processing to capture features of perturbed sleep in patients with a BD.METHODS: Seventy-four patients completed the AIS and the Quick Inventory of Depressive Symptomatology, self-report (QIDS-SR-16). Locomotor activity was continuously recorded by wrist actigraphy for ≥10 consecutive days. We computed the sleep onset/offset, the center of daily inactivity (CenDI), as a proxy for chronotype, and the degree of consolidation of daily inactivity (ConDI), as a proxy for sleep-wake rhythm strength.RESULTS: AIS showed good psychometric properties (Cronbach's alpha = 0.84; test-retest correlation = 0.84, P<.001). Subjective sleep problems correlated moderately with a later sleep phase (CenDI with AIS rho = 0.34, P = .003), lower consolidation (ConDI with AIS rho = -0.22, P = .05; with QIDS-SR-16 rho = -0.27, P = .019), later timing of sleep offset (with AIS rho = 0.49, P = ≤.001, with QIDS-SR-16 rho = 0.36, P = .002), and longer total sleep (with AIS rho = 0.29, P = .012, with QIDS-SR-16 rho = 0.41, P = ≤.001). While AIS was psychometrically more solid, correlations with objective sleep were more consistent across time for QIDS-SR-16.CONCLUSIONS: AIS and QIDS-SR-16 are suitable for clinical screening of sleep problems among patients with a BD. Subjective insomnia associated with objective measures. For clinical and research purposes, actigraphy and data visualization on inactograms are useful for accurate longitudinal characterization of sleep patterns.

DOI10.1111/bdi.12903
Alternate JournalBipolar Disord
PubMed ID32232937
Grant ListRGPIN-2015-04034 / / Natural Sciences and Engineering Research Council of Canada /
#366858 / / Canadian Institutes for Health Research /
#252872 / / Fonds de Recherche du Québec - Santé /
#8400863 / / Fonds de Recherche du Québec - Santé /