Electroencephalographic abnormalities and 5-year outcome in first-episode psychosis.
| Title | Electroencephalographic abnormalities and 5-year outcome in first-episode psychosis. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Manchanda R, Norman R, Malla A, Harricharan R, Northcott S, Richard J |
| Journal | Can J Psychiatry |
| Volume | 59 |
| Issue | 5 |
| Pagination | 285-8 |
| Date Published | 2014 May |
| ISSN | 0706-7437 |
| Keywords | Adaptation, Psychological, Adolescent, Adult, Child, Comorbidity, Educational Status, Electroencephalography, Female, Follow-Up Studies, Humans, Male, Ontario, Patient Outcome Assessment, Predictive Value of Tests, Psychiatric Status Rating Scales, Psychotic Disorders, Social Adjustment, Substance-Related Disorders |
| Abstract | OBJECTIVE: To examine the relation of electroencephalographic abnormalities to 5-year outcomes in first-episode psychosis (FEP).METHODS: Patients (n = 103) had their baseline electroencephalogram (EEG) classified by modified Mayo Clinic criteria. Symptoms and psychosocial functioning were rated after 5 years of treatment.RESULTS: Dysrhythmic EEG was associated with persistence in positive and negative symptoms of psychoses and poorer psychosocial functioning at 5-year follow-up, independently of other characteristics, such as duration of untreated illness or premorbid adjustment. A higher percentage of people with comorbid substance use disorder had normal EEG.CONCLUSIONS: Abnormal baseline EEG in FEP is associated with poorer 5-year symptomatic and functional outcome. |
| Alternate Journal | Can J Psychiatry |
| PubMed ID | 25007282 |
| PubMed Central ID | PMC4079140 |
| Grant List | MOP-57925 / / Canadian Institutes of Health Research / Canada |
