Development of a patient-reported outcome instrument to assess complex activities of daily living and interpersonal functioning in persons with mild cognitive impairment: The qualitative research phase.
|Title||Development of a patient-reported outcome instrument to assess complex activities of daily living and interpersonal functioning in persons with mild cognitive impairment: The qualitative research phase.|
|Publication Type||Journal Article|
|Year of Publication||2016|
|Authors||Gordon MForrest, Lenderking WR, Duhig A, Chandler J, J Lundy J, Miller DS, Piault-Louis E, Doody RS, Galasko D, Gauthier S, Frank L|
|Corporate Authors||Patient-Reported Outcome Consortium's Cognition Working Group|
|Date Published||2016 Jan|
|Keywords||Activities of Daily Living, Aged, Aged, 80 and over, Alzheimer Disease, Cognitive Dysfunction, Female, Humans, Interpersonal Relations, Male, Middle Aged, Neuropsychological Tests, Patient Outcome Assessment, Qualitative Research, Self Report|
INTRODUCTION: As drug development research efforts move toward studying patients earlier in the course of Alzheimer's disease (AD), it is important to incorporate the patient's perspective into measurement of outcomes.METHODS: This article summarizes the qualitative work of the Patient-Reported Outcome Consortium's Cognition Working Group in the development of a new self-reported outcome measure in persons with mild cognitive impairment (MCI) due to suspected AD, herein referred to as MCI.RESULTS: The draft measure captures the patient's voice for two functional domains, complex activities of daily living and interpersonal functioning.DISCUSSION: This work represents a series of initial steps in the development of this rating scale. The next steps are to conduct psychometric analysis and evaluate the role of insight.
|Alternate Journal||Alzheimers Dement|