Clinical Usefulness of Therapeutic Neuromodulation for Major Depression: A Systematic Meta-Review of Recent Meta-Analyses.

TitleClinical Usefulness of Therapeutic Neuromodulation for Major Depression: A Systematic Meta-Review of Recent Meta-Analyses.
Publication TypeJournal Article
Year of Publication2018
AuthorsMcGirr A, Berlim M
JournalPsychiatr Clin North Am
Volume41
Issue3
Pagination485-503
Date Published2018 Sep
ISSN1558-3147
Abstract

The authors conducted a meta-review of meta-analyses published in the past decade on therapeutic neuromodulation (ie, repetitive transcranial magnetic stimulation, transcranial direct current stimulation, vagus nerve stimulation and deep brain stimulation) for major depression. Active repetitive transcranial magnetic stimulation and transcranial direct current stimulation have been generally associated with small to moderate effect sizes vis-à-vis their efficacy and with similar acceptability compared with sham. Vagus nerve stimulation and deep brain stimulation (although more challenging to investigate) have demonstrated preliminary effectiveness, particularly during longer-term follow-up.

DOI10.1016/j.psc.2018.04.009
Alternate JournalPsychiatr. Clin. North Am.
PubMed ID30098660

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