Alain Brunet Ph.D.
6875 Boulevard LaSalle
Montréal QC
H4H 1R3
Chercheur, Centre de recherche Douglas
Professeur agrégé, Département de psychiatrie, Université McGill
Rédacteur adjoint, Journal of Traumatic Stress
Impact des psychotraumatismes sur la santé mentale
Pr Brunet étudie l’impact des psychotraumatismes sur la santé mentale. Il s’intéresse aux facteurs de risque et à la mise au point de traitements pour soigner le trouble de stress post-traumatique (TSPT). Il est également intéressé par l'épidémiologie et la neurobiologie du TSPT, ainsi qu'aux usages d'Internet en santé mentale.
Alain Brunet a mis au point, en 2001 un auto-questionnaire permettant d’évaluer l’intensité du stress vécu lors d'un événement traumatique. Ce questionnaire a été utilisé par des dizaines d'équipes dans le monde et a été traduit en 12 langues.
Un intérêt majeur du Pr Brunet provient d'une percée scientifique réalisée en collaboration avec ses collègues de McGill et de Harvard, soit l'usage d'un médicament, habituellement utilisé pour soigner la 'haute pression' artérielle, pour soigner le TSPT. Repenser à son trauma sous propranolol diminue par la suite l'intensité de ce souvenir et entraîne une baisse des symptômes de TSPT.
-Katzman, M.A., et al. (2014). Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders. BMC Psychiatry, 14 Suppl., 1:S1doi: 10.1186/1471-244X-14-S1-S1.
-Labonté, B., Azoulay, N., Yerko, V., Turecki, G., & Brunet, A. (2014). Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder. Translational Psychiatry, 4, 1-7. doi:10.1038/tp.2014.3.
-Lonergan MH, Olivera-Figueroa LA, Pitman RK, & Brunet A. (2013). Propranolol's effects on the consolidation and reconsolidation of long-term emotional memory in healthy participants: a meta-analysis. Journal of Psychiatry and Neuroscience, 38(4) PubMed ID: 23182304
-Bui E, Rodgers RF, Herbert C, Franko DL, Simon NM, Birmes P, Brunet A. (2012). The impact of internet coverage of the March 2011 Japan earthquake on sleep and posttraumatic stress symptoms: an international perspective. The American journal of psychiatry, 169(2) PubMed ID: 22318796
-LaGarde, G., Doyon, J., & BRUNET, A. (2010). Memory and executive dysfunctions associated with acute Posttraumatic Stress Disorder. Psychiatry Research, 177, 144-149.
-FRQ-S Chercheur boursier (2002-2012)
-Finaliste aux 10 découvertes de l'année - Québéc Sciences (2008)
-Fondation de la Recherche Médicale, France: Prix Jeune Chercheur (2006-8)
-Personnalité de la semaine - La Presse (2006)
-Palmarès Maclean's: 39 Canadiens qui ont changé le monde pour le mieux (2006)
-Prix Heinz-Lehmann (2003)
Daniel Saumier, Ph.D. (psychologue)
Christophe Herbert, M.A., (psychologue)
Jacques Tremblay, M.D.
Pr. Brunet remercie les étudiants et les bénévoles pour leur aide dans la gestion du labo.
Nouvelles
Publications récentes
-
On the Use of Memory Update Mechanisms to Treat Patients: Response to Waits and Hoge. Am J Psychiatry. 2018;175(11):1145-1146.
-
Reduction of PTSD Symptoms With Pre-Reactivation Propranolol Therapy: A Randomized Controlled Trial. Am J Psychiatry. 2018:appiajp201717050481.
-
Prenatal maternal stress is associated with toddler cognitive functioning: The Iowa Flood Study. Early Hum Dev. 2018;116:84-92.
-
Mental Disorder Symptoms among Public Safety Personnel in Canada. Can J Psychiatry. 2017:706743717723825.
-
The Effects of Prenatal Maternal Stress on Early Temperament: The 2011 Queensland Flood Study. J Dev Behav Pediatr. 2017;38(5):310-321.
-
Longitudinal analysis of quality of life across the trauma spectrum. Psychol Trauma. 2017;9(5):605-612.
-
Consolidation and reconsolidation are impaired by oral propranolol administered before but not after memory (re)activation in humans. Neurobiol Learn Mem. 2017;142(Pt A):118-125.
-
Assessing trauma and posttraumatic stress disorder: Single, open-ended question versus list-based inventory. Psychol Assess. 2016;28(8):1001-8.
-
Effects of Propranolol, a β-noradrenergic Antagonist, on Memory Consolidation and Reconsolidation in Mice. Front Behav Neurosci. 2016;10:49.
-
Place and Posttraumatic Stress Disorder. J Trauma Stress. 2016;29(4):293-300.
-
Psychometric Validation of the English and French Versions of the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5). PLoS ONE. 2016;11(10):e0161645.
-
Reactivating addiction-related memories under propranolol to reduce craving: A pilot randomized controlled trial. J Behav Ther Exp Psychiatry. 2016;50:245-9.
-
The effects of maternal stress and illness during pregnancy on infant temperament: Project Ice Storm. Pediatr Res. 2016;79(1-1):107-13.
-
Trauma Exposure and Posttraumatic Stress Disorder in the Canadian Military. Can J Psychiatry. 2015;60(11):488-96.
-
Peritraumatic Distress Mediates the Effect of Severity of Disaster Exposure on Perinatal Depression: The Iowa Flood Study. J Trauma Stress. 2015;28(6):515-22.
-
QF2011: a protocol to study the effects of the Queensland flood on pregnant women, their pregnancies, and their children's early development. BMC Pregnancy Childbirth. 2015;15:109.
-
Prenatal stress due to a natural disaster predicts adiposity in childhood: the Iowa Flood Study. J Obes. 2015;2015:570541.
-
Prenatal maternal stress predicts stress reactivity at 2½ years of age: the Iowa Flood Study. Psychoneuroendocrinology. 2015;56:62-78.
-
Domains of quality of life and social support across the trauma spectrum. Soc Psychiatry Psychiatr Epidemiol. 2015;50(8):1243-8.
-
Emotional face processing in post-traumatic stress disorder after reconsolidation impairment using propranolol: A pilot fMRI study. J Anxiety Disord. 2015;36:127-33.
-
Cohort Profile: The Nicotine Dependence in Teens (NDIT) Study. Int J Epidemiol. 2015;44(5):1537-46.
-
Suicide risk among active and retired Canadian soldiers: the role of posttraumatic stress disorder. Can J Psychiatry. 2014;59(9):457-9.
Publications récentes
-
On the Use of Memory Update Mechanisms to Treat Patients: Response to Waits and Hoge. Am J Psychiatry. 2018;175(11):1145-1146.
-
Reduction of PTSD Symptoms With Pre-Reactivation Propranolol Therapy: A Randomized Controlled Trial. Am J Psychiatry. 2018:appiajp201717050481.
-
Prenatal maternal stress is associated with toddler cognitive functioning: The Iowa Flood Study. Early Hum Dev. 2018;116:84-92.
-
Mental Disorder Symptoms among Public Safety Personnel in Canada. Can J Psychiatry. 2017:706743717723825.
-
The Effects of Prenatal Maternal Stress on Early Temperament: The 2011 Queensland Flood Study. J Dev Behav Pediatr. 2017;38(5):310-321.
-
Longitudinal analysis of quality of life across the trauma spectrum. Psychol Trauma. 2017;9(5):605-612.
-
Consolidation and reconsolidation are impaired by oral propranolol administered before but not after memory (re)activation in humans. Neurobiol Learn Mem. 2017;142(Pt A):118-125.
-
Assessing trauma and posttraumatic stress disorder: Single, open-ended question versus list-based inventory. Psychol Assess. 2016;28(8):1001-8.
-
Effects of Propranolol, a β-noradrenergic Antagonist, on Memory Consolidation and Reconsolidation in Mice. Front Behav Neurosci. 2016;10:49.
-
Place and Posttraumatic Stress Disorder. J Trauma Stress. 2016;29(4):293-300.
-
Psychometric Validation of the English and French Versions of the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5). PLoS ONE. 2016;11(10):e0161645.
-
Reactivating addiction-related memories under propranolol to reduce craving: A pilot randomized controlled trial. J Behav Ther Exp Psychiatry. 2016;50:245-9.
-
The effects of maternal stress and illness during pregnancy on infant temperament: Project Ice Storm. Pediatr Res. 2016;79(1-1):107-13.
-
Trauma Exposure and Posttraumatic Stress Disorder in the Canadian Military. Can J Psychiatry. 2015;60(11):488-96.
-
Peritraumatic Distress Mediates the Effect of Severity of Disaster Exposure on Perinatal Depression: The Iowa Flood Study. J Trauma Stress. 2015;28(6):515-22.
-
QF2011: a protocol to study the effects of the Queensland flood on pregnant women, their pregnancies, and their children's early development. BMC Pregnancy Childbirth. 2015;15:109.
-
Prenatal stress due to a natural disaster predicts adiposity in childhood: the Iowa Flood Study. J Obes. 2015;2015:570541.
-
Prenatal maternal stress predicts stress reactivity at 2½ years of age: the Iowa Flood Study. Psychoneuroendocrinology. 2015;56:62-78.
-
Domains of quality of life and social support across the trauma spectrum. Soc Psychiatry Psychiatr Epidemiol. 2015;50(8):1243-8.
-
Emotional face processing in post-traumatic stress disorder after reconsolidation impairment using propranolol: A pilot fMRI study. J Anxiety Disord. 2015;36:127-33.
-
Suicide risk among active and retired Canadian soldiers: the role of posttraumatic stress disorder. Can J Psychiatry. 2014;59(9):457-9.
-
Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders. BMC Psychiatry. 2014;14 Suppl 1:S1.
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