Loading Events

« All Events

  • This event has passed.

Carla Nasca

2023-05-26 @ 10:00 - 11:00 EDT

Please join us on May 26, 2023, at 10:00 AM for a Special Seminar hosted by Adversity and Mental Health.

*Note that this meeting will be held in person at the William E. Stavert Amphitheatre, Douglas Hall*


Carla Nasca, PhD
Assistant Professor, Department of Psychiatry, Department of Neuroscience & Physiology, NYU School of Medicine, New York
Head of Epigenetics & System Neuroscience Lab, NYU School of Medicine, New York
Blavatnik Awardee for Innovative Research


Epigenetic embedding of childhood adversity: mitochondrial metabolism and neurobiology of stress-related CNS diseases

Speaker Biography

At NYU School of Medicine, Dr. Nasca lab is working on an innovative framework of epigenetic mechanisms of neuroplasticity in stress responses and psychiatric disorders with a new angle on mitochondrial metabolism. Key to this framework is the pivotal mitochondrial metabolite L-acetylcarnitine (LAC), which she discovered as a novel epigenetic modulator of glutamatergic function and a therapeutic target for clinical phenotypes of treatment-resistant depression linked to childhood trauma. Using the novel exosome technology, her group further showed that modulating mitochondrial metabolism of LAC is predictive of changes in other important aspects of human physiology, such as insulin resistance. Further understanding of the cellular and molecular bases of mitochondrial mediators of epigenetic function may reveal surprising insights in a complex network of biological factors contributing to the risk for stress-related diseases, including depression, PTSD, and aging ultimately leading to personalized medicine strategies.

Dr. Nasca is Head of the laboratory of Epigenetics & System Neuroscience and Assistant Professor at NYU School of Medicine in New York in the Departments of Psychiatry and Neuroscience. She joined NYU after directing her own research group at Rockefeller University where she previously trained in Neuroscience with Bruce McEwen. She also received training in Translational Neuroscience from clinical colleagues at Stanford University. Currently active grants include a Reversibility Network on Childhood Adversity Award from the National Institute of Aging (NIA), a R01 and a R56 from the National Institute on Mental Health (NIMH), a Transformative High-Risk High-Reward Falk research grant, two NARSAD Young Investigator awards. She also is a recipient of the Blavatnik Award for Innovative Research.

Meet the speaker lunch

If you are a trainee and would like to meet the speaker, please contact coordinator@adversitymentalhealth.com

Unable to attend?

For those of you who cannot make it in person, the talk will be broadcast via Zoom.

Meeting ID: 854 1808 0299Passcode: 809976


10:00 - 11:00 EDT
Event Category:
Event Tags:


Douglas Hall, Douglas Institute
6875 Lasalle Blvd
Montreal, Quebec H4H 1R3 Canada
+ Google Map
View Venue Website