The brain in flux: Genetic, physiologic, and therapeutic perspectives on transporters in the CNS.

TitleThe brain in flux: Genetic, physiologic, and therapeutic perspectives on transporters in the CNS.
Publication TypeJournal Article
Year of Publication2019
AuthorsBlakely RD, Mestikawy SEl, Robinson MB
JournalNeurochem Int
Volume123
Pagination1-6
Date Published2019 Feb
ISSN1872-9754
Abstract

The brain has specific properties that make it uniquely dependent upon transporters. This is the 3rd edition of a biennial special issue that originates from a scientific meeting devoted to studies of transporters and their relationship to brain function and to neurodevelopmental, neurologic, and psychiatric disorders. The field continues to rapidly evolve with advances in studies of structure that inform mechanism, with genetic analyses in humans revealing surprising aspects of biology, and with integrated cellular to whole animal analyses of the role of transporters in their control of physiology and pathophysiology. This special issue includes a sampling of review articles that address timely questions of the field followed by several primary research articles.

DOI10.1016/j.neuint.2018.12.006
Alternate JournalNeurochem. Int.
PubMed ID30571999